{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:17:59Z","timestamp":1784330279535,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Regional Health Authority of North Norway"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare uterine artery volume blood flow (<jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content><jats:sub>uta<\/jats:sub>), vascular resistance (<jats:styled-content style=\"fixed-case\">R<\/jats:styled-content><jats:sub>uta<\/jats:sub>), pulsatility index (<jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>ta\u00a0<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>), and the fraction of maternal cardiac output (<jats:styled-content style=\"fixed-case\">CO<\/jats:styled-content>) distributed to the uteroplacental circulation in pregnant women with and without a previous caesarean section.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Cross\u2010sectional observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University hospital in Norway.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Thirty\u2010two pregnant women with previous caesarean section and 32 matched controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ultrasonography was used to measure uterine artery diameter and blood flow velocity between 22<jats:sup>+0<\/jats:sup> and 23<jats:sup>+6<\/jats:sup>\u00a0weeks of gestation. Impedance cardiography was used to assess maternal haemodynamics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content><jats:sub>uta<\/jats:sub>, <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content><jats:sub>uta<\/jats:sub>, <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>ta <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>, and the fraction of maternal <jats:styled-content style=\"fixed-case\">CO<\/jats:styled-content> distributed to the uteroplacental circulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content><jats:sub>uta<\/jats:sub> was 356.26\u00a0\u00b1\u00a0213.72\u00a0ml\/minute in cases and 456.41\u00a0\u00b1\u00a0209.70\u00a0ml\/minute in controls (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.038). <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content><jats:sub>uta<\/jats:sub> was significantly (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.026) higher among cases compared with controls (0.32\u00a0\u00b1\u00a00.20 versus 0.22\u00a0\u00b1\u00a00.14\u00a0mmHg\/ml\/minute), but the <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>ta\u00a0<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> did not differ between the groups (0.93\u00a0\u00b1\u00a00.23 versus 0.92\u00a0\u00b1\u00a00.47; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.929). The fraction of maternal <jats:styled-content style=\"fixed-case\">CO<\/jats:styled-content> distributed to the uteroplacental circulation was 5.75\u00a0\u00b1\u00a03.68% in cases and 8.45\u00a0\u00b1\u00a05.02% in controls (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.014).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Uterine artery volume blood flow and the fraction of maternal cardiac output distributed to the uteroplacental circulation are lower, and uterine vascular resistance (but not <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>ta <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) is higher, in women with previous caesarean section compared with the control group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12441","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:51:07Z","timestamp":1381542667000},"page":"210-215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Blood flow to the scarred gravid uterus at 22\u201324\u00a0weeks of gestation"],"prefix":"10.1111","volume":"121","author":[{"given":"K","family":"Flo","sequence":"first","affiliation":[{"name":"Women's Health and Perinatology Research Group Department of Clinical Medicine Faculty of Health Sciences University of Troms\u00f8 Troms\u00f8 Norway"},{"name":"Department of Obstetrics and Gynaecology University Hospital of North Norway Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Widnes","sequence":"additional","affiliation":[{"name":"Women's Health and Perinatology Research Group Department of Clinical Medicine Faculty 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