{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T02:33:06Z","timestamp":1777084386460,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,1]]},"abstract":"\n Objective<\/jats:title>\n To investigate the anatomical cure rate and complications related to collagen\u2010coated mesh for cystocele, compared with a conventional anterior colporrhaphy.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n A randomised controlled study.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Six departments of obstetrics and gynaecology in Norway, Sweden, Finland, and Denmark.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n Women aged 55\u00a0years or older, referred for surgery with a prolapse of the anterior vaginal wall of stage\u00a02 or higher.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Women scheduled for primary cystocoele surgery were randomised to either anterior colporrhaphy or a collagen\u2010coated Prolene mesh. Power analysis indicated that 130 patients had to be randomised. All patients were evaluated using the Pelvic Organ Prolapse\u2010Quantification (\n POP<\/jats:styled-content>\n \u2010Q) measurement. Quality of life, symptoms, and sexual function were evaluated using the Pelvic Floor Impact Questionnaire, the Pelvic Floor Distress Inventory, and the Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire.\n <\/jats:p>\n <\/jats:sec>\n \n Main outcome measures<\/jats:title>\n \n The primary outcome was objective cure, defined as prolapse below\n POP<\/jats:styled-content>\n \u2010Q stage\u00a02 at the 12\u2010months follow\u2010up. Secondary outcomes were quality of life, symptoms, and presence (or not) of complications.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n In total, 161 women were randomised to either anterior colporrhaphy or mesh (participant ages 64.9\u00a0\u00b1\u00a06.4\u00a0years versus 64.7\u00a0\u00b1\u00a06.6\u00a0years, respectively; mean\u00a0\u00b1\u00a0\n SD<\/jats:styled-content>\n ). The objective cure rate was 39.8% (95%\u00a0\n CI<\/jats:styled-content>\n 28.6\u201350.9%) in the anterior colporrhaphy group, compared with 88.1% (95%\u00a0\n CI<\/jats:styled-content>\n 80.7\u201395.6%) in the mesh group (\n P<\/jats:italic>\n \u00a0<\u00a00.001). Vaginal mesh exposure occurred in ten women (13.3%) and dyspareunia occurred in two women (2.7%, not significant) in the mesh group at the 12\u2010months follow\u2010up. Questionnaires revealed no difference between the groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Our study demonstrates a significantly improved objective cure rate associated with a high exposure rate among women with mesh surgery as opposed to conventional surgery.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1471-0528.12454","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T21:26:49Z","timestamp":1381526809000},"page":"102-111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Anterior colporrhaphy compared with collagen\u2010coated transvaginal mesh for anterior vaginal wall prolapse: a randomised controlled trial"],"prefix":"10.1111","volume":"121","author":[{"given":"M","family":"Rudnicki","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Roskilde University Hospital Roskilde Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Laurikainen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Turku University Hospital Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Pogosean","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Lidk\u00f6ping Hospital Lidk\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Kinne","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Ahus University Hospital Ahus Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Jakobsson","sequence":"additional","affiliation":[{"name":"Center for Primary Healthcare Research Faculty of Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Teleman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Skane University Hospital Lund Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00058-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.119081"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31816a2489"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-1018-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1153-x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318237edc4"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009521"},{"issue":"360","key":"e_1_2_7_9_1","first-page":"e1","article-title":"Laparoscopic sacral colpopey versus total vaginal mesh for vaginal vault prolapse: a randomized trial","volume":"204","author":"Maher CF","year":"2011","journal-title":"Am J Obstet Gynecol"},{"issue":"83","key":"e_1_2_7_10_1","first-page":"e1","article-title":"Surgical intervention after transvaginal Prolift mesh repair: retrospective single\u2010center study including 524 patients with 3\u00a0years' median follow\u2010up","volume":"206","author":"Landsheere L","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02254.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03082.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.21064"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2007.02.003"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.12.029"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2011.01.027"},{"key":"e_1_2_7_17_1","unstructured":"[http:\/\/www.fda.gov\/downloads\/advisorycommittees\/committeesmeetingmaterials\/medicaldevices\/medicaldevicesadvisorycommittee\/obstetricsandgynecologydevices\/ucm270402.pdf]. Accessed 17 September 2013."},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(00)00859-0"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181b2b1ae"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.025"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-003-1063-2"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0465-y"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s0192-005-0041-2"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000250970.23128.63"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22231"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91562-O"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.03.030"}],"container-title":["BJOG: An International Journal of Obstetrics & Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.12454","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.12454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T03:45:25Z","timestamp":1696218325000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.12454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/1471-0528.12454"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.12454","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718141483.793488600","asserted-by":"object"}]},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"2013-06-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}