{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T07:38:39Z","timestamp":1769499519273,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T00:00:00Z","timestamp":1382400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether termination of pregnancy (<jats:styled-content style=\"fixed-case\">TOP<\/jats:styled-content>), including the method used or gestational age at termination, affects future obstetric and perinatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Register\u2010based cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Aberdeen Maternity Hospital, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cotland, <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>From the Aberdeen Maternity and Neonatal Databank (<jats:styled-content style=\"fixed-case\">AMND<\/jats:styled-content>) we identified 3186 women who had terminated their first pregnancy and then had a second pregnancy of beyond 24\u00a0weeks of gestation between 1986 and 2010. We identified 42\u00a0446 women who had their first delivery in the same time period, for comparison.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Univariate and multivariate logistic regression was used to compare outcomes between groups. Complete case analysis with adjustment of confounding factors was carried out, and adjusted odds ratios (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>s) with 99% confidence intervals are presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The primary outcome was spontaneous preterm delivery (<jats:styled-content style=\"fixed-case\">SPTD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No statistically significant association was found between TOP in the first pregnancy and SPTD in the next pregnancy (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.05; 99%\u00a0CI 0.83\u20131.32). Neither medical (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.03; 99%\u00a0CI 0.72\u20131.46) nor surgical (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.06; 99%\u00a0CI 0.78\u20131.44) termination appeared to affect the risk of spontaneous preterm delivery in the subsequent pregnancy. Late termination (\u226513\u00a0weeks of gestation) did not appear to increase the risk of spontaneous preterm delivery compared with early termination (&lt;13\u00a0weeks of gestation) (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.65; 99%\u00a0CI 0.94\u20132.92), nor compared with primigravid women (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.25; 99%\u00a0CI 0.97\u20131.62). There was an associated increased risk of antepartum haemorrhage in the next pregnancy following TOP (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01; <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.26; 99%\u00a0CI 1.10\u20131.45).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Evidence on obstetric and perinatal outcomes following <jats:styled-content style=\"fixed-case\">TOP<\/jats:styled-content> remains conflicting. This study suggests that <jats:styled-content style=\"fixed-case\">TOP<\/jats:styled-content> is not associated with an increased risk of spontaneous preterm delivery. Neither the method nor the gestational age of <jats:styled-content style=\"fixed-case\">TOP<\/jats:styled-content> has any effect on this lack of association.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12455","type":"journal-article","created":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T16:09:04Z","timestamp":1382458144000},"page":"309-318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The effect of method and gestational age at termination of pregnancy on future obstetric and perinatal outcomes: a register\u2010based cohort study in <scp>A<\/scp>berdeen, <scp>S<\/scp>cotland"],"prefix":"10.1111","volume":"121","author":[{"given":"A","family":"Woolner","sequence":"first","affiliation":[{"name":"Obstetrics &amp; Gynaecology Division of Applied Health Sciences School of Medicine and Dentistry University of Aberdeen Aberdeen UK"},{"name":"Department of Obstetrics &amp; Gynaecology Aberdeen Maternity Hospital and Aberdeen Royal Infirmary NHS Grampian Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Obstetrics &amp; Gynaecology Division of Applied Health Sciences School of Medicine and Dentistry University of Aberdeen Aberdeen UK"},{"name":"Department of Obstetrics &amp; Gynaecology Aberdeen Maternity Hospital and Aberdeen Royal Infirmary NHS Grampian Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soh","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Obstetric Epidemiology Dugald Baird Centre for Research on Women's Health Aberdeen Maternity Hospital Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,22]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Royal College of Obstetricians and Gynaecologists.The Care of Women Requesting Induced Abortion: Summary. 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