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In microbial autophagy degraded peptides are used to induce antigen\u2010specific acquired immunity. Viruses, bacteria, fungi, and protozoa have developed strategies to subvert autophagy and\/or to use this process to promote their replication and persistence. This review details the mechanisms by which microorganisms that infect the female genital tract and\/or are detrimental to pregnancy interact with this host defence mechanism. 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