{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T05:29:27Z","timestamp":1768714167054,"version":"3.49.0"},"reference-count":57,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Hydrosalpinges in infertile women reduce the success of <jats:italic>in vitro<\/jats:italic> fertilisation (<jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>) by 50%. Surgical management of hydrosalpinges before <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content> improves outcome but these procedures are often contraindicated in women with dense pelvic adhesions. Tubal occlusion achieved by <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup> via hysteroscopy provides an alternative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To conduct a systematic review on the efficacy and safety of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup> in the management of hydrosalpinx before <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Search strategy<\/jats:title><jats:p>We searched <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content> (January 1950 to July 2013), <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content> (January 1980 to July 2013) and Web of Science (1899 to July 2013). We also searched reference lists of relevant articles and proceedings of relevant international conferences (2000\u20132013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Selection criteria<\/jats:title><jats:p>All types of studies where women with suspected infertility and presence of hydrosalpinx had hysteroscopic tubal occlusion with <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup> before <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data collection and analysis<\/jats:title><jats:p>Two authors independently selected studies and extracted data. Where necessary, study authors were contacted for further data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main results<\/jats:title><jats:p>In all, 115 women in 11 studies received <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup>, mainly in the outpatient setting where local anaesthesia by paracervical block and\/or intravenous sedation was used. Successful placement of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup> was achieved in 96.5% (95% confidence interval [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 91.1\u201398.9%) of women and tubal occlusion in 98.1% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 93.1\u201399.9%). Subsequent <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content> resulted in 38.6% pregnancy rate (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 30.9\u201346.8%), 27.9% live birth rate (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 21.1\u201335.8%) and 28.6% combined ongoing pregnancy and live birth rate (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 21.7\u201336.6%) per embryo transfer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Author's conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ssure<jats:sup>\u00ae<\/jats:sup> appears to be an effective option for management of hydrosalpinx in women before <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content> although evidence from a randomised controlled clinical trial is lacking.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12533","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T06:50:49Z","timestamp":1388731849000},"page":"527-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Essure<sup>\u00ae<\/sup> for management of hydrosalpinx prior to <i>in vitro<\/i> fertilisation\u2014a systematic review and pooled analysis"],"prefix":"10.1111","volume":"121","author":[{"given":"P","family":"Arora","sequence":"first","affiliation":[{"name":"Department of Reproductive Medicine St Mary's Hospital Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RS","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Max Super Speciality Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Cahill","sequence":"additional","affiliation":[{"name":"Academic Unit of Obstetrics and Gynaecology St Michael's Hospital Bristol UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138362"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)80079-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)58398-8"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)00447-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a138606"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/14.5.1243"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(98)00200-3"},{"key":"e_1_2_7_9_1","first-page":"CD002125","article-title":"Surgical treatment for tubal disease in women due to undergo in vitro fertilisation","author":"Johnson N","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.08.089"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2013.03.008"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2009.07.026"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.02.080"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.10.056"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/2685469"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"key":"e_1_2_7_17_1","unstructured":"WellsGA SheaB O'ConnellD PetersonJ WelchV LososM et\u00a0al.The Newcastle\u2010Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analyses. 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