{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T06:48:33Z","timestamp":1781160513453,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T00:00:00Z","timestamp":1389571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the initial placement of Elevate single\u2010incision mesh kit device tips relative to the sacrospinous ligament, and to measure tip movement over a 6\u2010month period from initial placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care urogynaecology centre in Calgary, Canada.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Women electing for surgical management of anterior vaginal wall prolapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten women underwent anterior prolapse repair using the Elevate single\u2010incision mesh kit with a metallic fiducial marker attached to the tips of the surgical device. Women were imaged by magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) within 48\u00a0hours of surgery, and again 6\u00a0months later to investigate the position of the device tips and change \u22654\u00a0mm over the 6\u2010month postoperative period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure(s)<\/jats:title><jats:p>Position of self\u2010fixating tips within 48 hours of surgery, and at six months post\u2010operative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Anchor insertion was directly into the sacrospinous ligament in 10 of 20 insertion points (50%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 27\u201373%). Movement was most often noted in the cranial\u2010caudal direction: a change in location of \u22654\u00a0mm was observed for 8\/20 anchors (40%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 19\u201364%). Cranial\u2010caudal movement was observed less frequently among sacrospinous anchors than among anchors inserted into other pelvic structures (1\/10 versus 7\/10, <jats:italic>P\u00a0<\/jats:italic>=\u00a00.020, difference in proportion \u221260%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u221294 to \u221226%). <jats:styled-content style=\"fixed-case\">PFDI<\/jats:styled-content>\u201020 scores improved statistically significantly by 6\u00a0months (<jats:italic>P\u00a0<\/jats:italic>=\u00a00.008, mean change \u221262.9%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u2212105.1 to \u221220.7%), but <jats:styled-content style=\"fixed-case\">PFIQ<\/jats:styled-content>\u20107 scores did not change statistically significantly over the same time period (<jats:italic>P\u00a0<\/jats:italic>=\u00a00.523, mean change \u221212.4%, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u221254.5 to 29.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The novel self\u2010fixating anchoring tips of this single\u2010incision mesh kit do not reliably anchor into the sacrospinous ligament. The tips have been shown to move with time, although not all cases of anchor movement were associated with recurrent prolapse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12536","type":"journal-article","created":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T06:09:11Z","timestamp":1389593351000},"page":"634-640","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Anchor placement and subsequent movement in a mesh kit with self\u2010fixating tips: 6\u2010month follow\u2010up of a prospective cohort"],"prefix":"10.1111","volume":"121","author":[{"given":"EA","family":"Brennand","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Bhayana","sequence":"additional","affiliation":[{"name":"Department of Radiology &amp; Diagnostic Imaging University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Birch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Cenaiko","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Robert","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology University of Calgary Calgary AB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-011-1542-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12040"},{"key":"e_1_2_7_4_1","unstructured":"FDA.FDA safety communication: UPDATE on serious complications associated with transvaginal placement of surgical mesh for pelvic organ prolapse.2011[www.fda.gov\/MedicalDevices\/Safety\/AlertsandNotices\/ucm262435.htm]. Accessed 11 March 2013."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2009.19"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-011-1536-7"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000250970.23128.63"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/GCO.0b013e32834a92ab","article-title":"Synthetic vaginal mesh for pelvic organ prolapse","volume":"23","author":"Iglesia CB","year":"2011","journal-title":"Curr Opin Obstet Gynecol"},{"key":"e_1_2_7_9_1","unstructured":"FDA.Medical device. Premarket notification (510k).2010[www.fda.gov\/MedicalDevices\/DeviceRegulationandGuidance\/HowtoMarketYourDevice\/PremarketSubmissions\/PremarketNotification510k\/default.htm]. Acessed 11 March 2013."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0b013e318278cc29"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.025"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-003-1063-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-011-1554-5"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1673-7"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.12536","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.12536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:02:06Z","timestamp":1695513726000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.12536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,13]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/1471-0528.12536"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.12536","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,13]]},"assertion":[{"value":"2013-10-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}