{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:35:04Z","timestamp":1776321304229,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T00:00:00Z","timestamp":1395187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,10]]},"abstract":"Objectives<\/jats:title>To expand the anatomical investigations of the G<\/jats:styled-content>\u2010spot and to assess the G<\/jats:styled-content>\u2010spot's characteristic histological and immunohistochemical features.<\/jats:p><\/jats:sec>Design<\/jats:title>An observational study.<\/jats:p><\/jats:sec>Setting<\/jats:title>International multicentre.<\/jats:p><\/jats:sec>Population<\/jats:title>Eight consecutive fresh human female cadavers.<\/jats:p><\/jats:sec>Methods<\/jats:title>Anterior vaginal wall dissections were executed and G<\/jats:styled-content>\u2010spot microdissections were performed. All specimens were stained with haematoxylin and eosin (H<\/jats:styled-content>&E<\/jats:styled-content>). The tissues of two women were selected at random for immunohistochemical staining.<\/jats:p><\/jats:sec>Main outcome measures<\/jats:title>The primary outcome measure was to document the anatomy of the G<\/jats:styled-content>\u2010spot. The secondary outcome measures were to identify the histology of the G<\/jats:styled-content>\u2010spot and to determine whether histological samples stained with H<\/jats:styled-content>&E<\/jats:styled-content> are sufficient to identify the G<\/jats:styled-content>\u2010spot.<\/jats:p><\/jats:sec>Results<\/jats:title>The anatomical existence of the G<\/jats:styled-content>\u2010spot was identified in all women and was in a diagonal plane. In seven (87.5%) and one (12.5%) of the women the G<\/jats:styled-content>\u2010spot complex was found on the left or right side, respectively. The G<\/jats:styled-content>\u2010spot was intimately fused with vessels, creating a complex. A large tangled vein\u2010like vascular structure resembled an arteriovenous malformation and there were a few smaller feeding arteries. A band\u2010like structure protruded from the tail of the G<\/jats:styled-content>\u2010spot. The size of the G<\/jats:styled-content>\u2010spot varied. Histologically, the G<\/jats:styled-content>\u2010spot was determined as a neurovascular complex structure. The neural component contained abundant peripheral nerve bundles and a nerve ganglion. The vascular component comprised large vein\u2010like vessels and smaller feeding arteries. Circular and longitudinal muscles covered the G<\/jats:styled-content>\u2010complex.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The anatomy of the G<\/jats:styled-content>\u2010spot complex was confirmed. The histology of the G<\/jats:styled-content>\u2010spot presents as neurovascular tissues with a nerve ganglion. H<\/jats:styled-content>&E<\/jats:styled-content> staining is sufficient for the identification of the G<\/jats:styled-content>\u2010spot complex.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12707","type":"journal-article","created":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T07:21:21Z","timestamp":1395213681000},"page":"1333-1340","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Verification of the anatomy and newly discovered histology of the G<\/scp>\u2010spot complex"],"prefix":"10.1111","volume":"121","author":[{"given":"A","family":"Ostrzenski","sequence":"first","affiliation":[{"name":"Institute of Gynecology Inc. 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