{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:04:45Z","timestamp":1761807885860},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,5,19]],"date-time":"2014-05-19T00:00:00Z","timestamp":1400457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIHR executive fellowship award","award":["NK"],"award-info":[{"award-number":["NK"]}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether a midwife\u2010led intervention improved preparation for twin parenting and maternal psychosocial outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Randomised controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Two maternity units in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orth <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ast <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ngland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A cohort of 162 women with uncomplicated twin pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Self\u2010completion questionnaire at multiple time points.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The primary outcome was probable postnatal depression (measured with the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>dinburgh <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ostnatal <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epression <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale, <jats:styled-content style=\"fixed-case\">EPDS<\/jats:styled-content>) 26\u00a0weeks after delivery. Secondary outcomes included preparation for parenting, maternal anxiety, parenting stress, and maternal wellbeing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean maternal <jats:styled-content style=\"fixed-case\">EPDS<\/jats:styled-content> scores at 26\u00a0weeks after delivery were 5.4 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a04.5) in the twin intervention (<jats:styled-content style=\"fixed-case\">TI<\/jats:styled-content>) group and 6.9 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a05.5) in the twin control (<jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>) group, and the mean difference between the groups was 1.5 (95% confidence interval, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, \u22120.2 to 3.3). The relative risk (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>) of having probable depression in the <jats:styled-content style=\"fixed-case\">TI<\/jats:styled-content> group compared with the <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content> group at 26\u00a0weeks was 0.48 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.19\u20131.20) for mothers and 0.84 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.42\u20131.70) for fathers. There were no statistically significant differences in maternal anxiety or parenting stress. <jats:styled-content style=\"fixed-case\">TI<\/jats:styled-content> mothers reported increased maternal wellbeing, reaction to motherhood, family support, mood, and greater self\u2010confidence 26\u00a0weeks after delivery, and felt more prepared for parenting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As a result of the limited sample size, the study was unable to detect a difference in maternal depression using the maternal <jats:styled-content style=\"fixed-case\">EPDS<\/jats:styled-content> mean score. The antenatal preparation for parenting programme did not improve postnatal maternal anxiety or parenting stress; however, it did improve postnatal maternal wellbeing, mood, self\u2010confidence, reaction to motherhood, and better prepared mothers to parent twin infants. 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