{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:43:24Z","timestamp":1791045804508,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T00:00:00Z","timestamp":1396828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Division of Obstetrics and Gynaecology"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate whether defective placentation disorders, i.e. pre\u2010eclampsia, stillbirth, small for gestational age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>), and spontaneous preterm birth, are associated with risk of retained placenta.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Population\u2010based cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Primiparous women in Sweden with singleton vaginal deliveries between 1997 and 2009 at 32\u201341\u00a0weeks of gestation (<jats:italic>n<\/jats:italic>\u00a0=\u00a0386\u00a0607), without placental abruption or infants with congenital malformations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Risks were calculated as odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s) by unconditional logistic regression with 95% confidence intervals (95%\u00a0<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s) after adjustments for maternal, delivery, and infant characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>Retained placenta, defined by the presence of both a diagnostic code (of retained placenta) and a procedure code (for the manual removal of the placenta).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall rate of retained placenta was 2.17%. The risk of retained placenta was increased for women with pre\u2010eclampsia (adjusted OR, <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>, 1.37, 95%\u00a0CI 1.21\u20131.54), stillbirth (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.71, 95%\u00a0CI 1.28\u20132.29), SGA birth (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.47, 95%\u00a0CI 1.28\u20131.70), and spontaneous preterm birth (32\u201334\u00a0weeks of gestation, <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a02.35, 95%\u00a0CI 1.97\u20132.81; 35\u201336\u00a0weeks of gestation, <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.55, 95%\u00a0CI 1.37\u20131.75). The risk was further increased for women with preterm pre\u2010eclampsia (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.69, 95%\u00a0CI 1.25\u20132.28) and preterm SGA birth (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a02.19, 95%\u00a0CI 1.42\u20133.38). There was no association between preterm stillbirth (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\u00a01.10, 95%\u00a0CI 0.63\u20131.92) and retained placenta, but the exposed group comprised only 15 cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Defective placentation disorders are associated with an increased risk of retained placenta. Whether these relationships indicate a common pathophysiology remains to be investigated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12752","type":"journal-article","created":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T06:54:51Z","timestamp":1396853691000},"page":"1462-1470","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Retained placenta is associated with pre\u2010eclampsia, stillbirth, giving birth to a small\u2010for\u2010gestational\u2010age infant, and spontaneous preterm birth: a national register\u2010based study"],"prefix":"10.1111","volume":"121","author":[{"given":"M","family":"Endler","sequence":"first","affiliation":[{"name":"Department of Clincal Science and Education Division of Obstetrics and Gynaecology Karolinska Institutet S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Saltvedt","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Division of Obstetrics and Gynaecology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Cnattingius","sequence":"additional","affiliation":[{"name":"Department of Medicine Clinical Epidemiology Unit Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Stephansson","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Division of Obstetrics and Gynaecology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Medicine Clinical Epidemiology Unit Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A\u2010K","family":"Wikstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Medicine Clinical Epidemiology Unit Karolinska Institutet Stockholm Sweden"},{"name":"Department of Women's and Children's Health Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2010.531301"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31824acb3b"},{"key":"e_1_2_6_4_1","first-page":"863","article-title":"Prolonged third stage of labor: morbidity and risk factors","volume":"77","author":"Combs CA","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181d74898"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00327-N"},{"key":"e_1_2_6_7_1","first-page":"CD004737","article-title":"Methods of delivering the placenta at caesarean section","author":"Anorlu RI","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349709047821"},{"key":"e_1_2_6_9_1","first-page":"532","article-title":"Risk factors for retained placenta in southwestern Nigeria","volume":"49","author":"Owolabi AT","year":"2008","journal-title":"Singapore Med J"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.009"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml016"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.526158"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2001.0650"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2010.10.016"},{"key":"e_1_2_6_15_1","unstructured":"Nordstr\u00f6mL. 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