{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T06:25:37Z","timestamp":1773296737875,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T00:00:00Z","timestamp":1397606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the oncological outcome and long\u2010term complications of radical surgery by robot\u2010assisted laparoscopy in early stage cervical cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Observational cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary referral centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>About 100 cervical cancer patients treated consecutively with robot\u2010assisted radical surgery between 2008 and 2013.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two gynaecological oncologists specialised in minimally invasive surgery performed all surgeries on a three\/four\u2010armed robotic system. Procedures consisted of pelvic lymph node dissection combined with a radical hysterectomy, radical vaginal trachelectomy or parametrectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Recurrence, survival and long\u2010term complication rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>104 robot\u2010assisted laparoscopies were performed in 100 patients (stage <jats:styled-content style=\"fixed-case\">IA<\/jats:styled-content>1\u2013<jats:styled-content style=\"fixed-case\">IIB<\/jats:styled-content>), with a median follow\u2010up of 29.5\u00a0months (range 2.5\u201367.1\u00a0months). Thirteen cases were diagnosed with a loco\u2010regional (8%), distant (4%) or combined (1%) recurrence at a median of 14.4\u00a0months (range 2.9\u201334.8\u00a0months). All mortality (7%) was cervical cancer\u2010related and due to recurrent disease. Four recurrences receive palliative care and two are in complete remission. The overall 5\u2010year progression\u2010free and disease\u2010specific survival rates are 81.4 and 88.7%, respectively. Frequent complications were lymphoedema (26%), lower urinary tract symptoms (19%), urinary tract infection (17%) and sexual disorders (9%). Five patients had a vaginal cuff dehiscence. No complication\u2010related mortality occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The recurrence, survival and long\u2010term complication rates of robot\u2010assisted radical surgery for early stage cervical cancer in this cohort are reassuring concerning its continued clinical use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12822","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T06:44:41Z","timestamp":1397630681000},"page":"1538-1545","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Oncological outcome and long\u2010term complications in robot\u2010assisted radical surgery for early stage cervical cancer: an observational cohort study"],"prefix":"10.1111","volume":"121","author":[{"given":"JP","family":"Hoogendam","sequence":"first","affiliation":[{"name":"Department of Gynaecological Oncology Woman and Baby Division University Medical Centre Utrecht Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RHM","family":"Verheijen","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology Woman and Baby Division University Medical Centre Utrecht Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Wegner","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology Woman and Baby Division University Medical Centre Utrecht Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RP","family":"Zweemer","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology Woman and Baby Division University Medical Centre Utrecht Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70084-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2012.08.035"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.11.037"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)02250-2"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00280.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2000.5860"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199905063401802"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00601.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004640000306"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(03)00518-3"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70369-8"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1995.0022"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(87)80002-1"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.11.037"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10397-010-0572-5"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.06.058"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.01.011"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-012-0270-8"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.07.025"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2009.06.024"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1611-9"},{"key":"e_1_2_6_23_1","unstructured":"European Organization for Research and Treatment of Cancer (EORTC).Chemotherapy followed by surgery versus radiotherapy plus chemotherapy in patients with stage IB or II cervical cancer. 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