{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T14:34:55Z","timestamp":1771511695732,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"s5","license":[{"start":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T00:00:00Z","timestamp":1413849600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD048330"],"award-info":[{"award-number":["R01HD048330"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The pipeline of vaginal microbicides for <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> prevention has expanded to include products for multipurpose prevention, but the interests of potential users and those advising on use have not been sufficiently investigated. Rather, assumptions about interest in multipurpose prevention technologies (<jats:styled-content style=\"fixed-case\">MPT<\/jats:styled-content>s) are inferred from what is known about acceptability and use of microbicides or contraceptives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and setting<\/jats:title><jats:p>This paper presents data on concerns and preferences for multipurpose prevention of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and pregnancy. Data were collected in two microbicide gel studies in Malawi and Zimbabwe. Participants were women using candidate vaginal products, their male partners, health professionals and community stakeholders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An individual interview was conducted with participants. Interviews were audio\u2010recorded, transcribed, coded for content and analysed for key themes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants indicated strong interest in a vaginal <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> prevention product that could also prevent pregnancy. Reasons for this interest were convenience, problems with adverse effects with current contraceptive methods, concerns about long\u2010term effects of contraceptives, and concerns about the health burdens of <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection during pregnancy. The main disadvantage of an <jats:styled-content style=\"fixed-case\">MPT<\/jats:styled-content> was recognition that while interest in preventing <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> is constant, contraceptive needs change over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study population indicated support for an <jats:styled-content style=\"fixed-case\">MPT<\/jats:styled-content> to prevent <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> and pregnancy. This support may be further strengthened if the product is also available for prevention of only <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>. Women and men will be more willing to use an <jats:styled-content style=\"fixed-case\">MPT<\/jats:styled-content> if they can be reassured that its use will have no long\u2010term effect on fertility.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12875","type":"journal-article","created":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T10:20:05Z","timestamp":1414491605000},"page":"45-52","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Interest in multipurpose prevention of <scp>HIV<\/scp> and pregnancy: perspectives of women, men, health professionals and community stakeholders in two vaginal gel studies in southern Africa"],"prefix":"10.1111","volume":"121","author":[{"given":"C","family":"Woodsong","sequence":"first","affiliation":[{"name":"International Partnership for Microbicides Silver Spring MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Musara","sequence":"additional","affiliation":[{"name":"UZ\u2010UCSF Collaborative Research Programme Harare Zimbabwe"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Chandipwisa","sequence":"additional","affiliation":[{"name":"UZ\u2010UCSF Collaborative Research Programme Harare Zimbabwe"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Montgomery","sequence":"additional","affiliation":[{"name":"RTI International San Franscisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Alleman","sequence":"additional","affiliation":[{"name":"USAID Office of Population and Reproductive Health Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Chirenje","sequence":"additional","affiliation":[{"name":"UZ\u2010UCSF Collaborative Research Programme Harare Zimbabwe"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Chipato","sequence":"additional","affiliation":[{"name":"UZ\u2010UCSF Collaborative Research Programme Harare Zimbabwe"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Martinson","sequence":"additional","affiliation":[{"name":"University of North Carolina Project Lilongwe Malawi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Hoffman","sequence":"additional","affiliation":[{"name":"University of North Carolina UNC Hospitals Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,21]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"790154","article-title":"Developing multipurpose reproductive health technologies: an integrated strategy","volume":"2013","author":"Harrison PF","year":"2013","journal-title":"AIDS Res Treat"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3182986f80"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2009.11.009"},{"key":"e_1_2_7_5_1","unstructured":"CAMI Health.MPT Database 2014. 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