{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:37:07Z","timestamp":1754109427375},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T00:00:00Z","timestamp":1408406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"University of Bergen and the Unger-Vetlesen Medical Foundation"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify high\u2010risk fetuses at the first routinely performed ultrasound examination by making use of information from the mother's previous pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A population\u2010based cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Norway, 1999\u20132009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>All singleton first live births and their second\u2010born siblings registered in the Medical Birth Registry of Norway (166\u00a0786 eligible sibling pairs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Odds ratios were calculated by logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Very small for gestational age (<jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content>; birthweight \u2264\u22121.96 standard deviations) and perinatal death (stillbirth at \u226522\u00a0weeks of gestation or death within 28\u00a0days of life).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Small fetal size at ultrasound (i.e. a fetus smaller than expected by last menstrual period, LMP) is only weakly predictive of <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content> or perinatal death; however, if the firstborn sibling was <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content> at birth, ultrasound measures in the next pregnancy become strongly informative of risk. The smaller the fetal size on ultrasound, the higher its risk of <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content> (3\u201318%; <jats:italic>P<\/jats:italic><jats:sub>trend<\/jats:sub>\u00a0&lt;\u00a00.0001) and perinatal death (4\u201319 per thousand, <jats:italic>P<\/jats:italic><jats:sub>trend<\/jats:sub>\u00a0=\u00a00.012). In contrast, if the first baby was not <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content>, small fetal size on ultrasound is uninformative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>When the firstborn baby is <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content>, discrepancies between fetal size on ultrasound and LMP become highly predictive of risk of <jats:styled-content style=\"fixed-case\">vSGA<\/jats:styled-content> and perinatal mortality in the second\u2010born infant. The value of combining these routinely\u00a0collected clinical data has not previously been recognised.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.13022","type":"journal-article","created":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T07:23:13Z","timestamp":1408432993000},"page":"1674-1681","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound prediction of perinatal outcome: the unrecognised value of sibling data"],"prefix":"10.1111","volume":"122","author":[{"given":"N\u2013H","family":"Morken","sequence":"first","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"},{"name":"Department of Clinical Sciences University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Skjaerven","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"},{"name":"Norwegian Institute of Public Health Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AJ","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Epidemiology Branch NIEHS\/NIH Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,19]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"613","article-title":"Routine ultrasound screening for the prediction of gestational age","volume":"65","author":"Campbell S","year":"1985","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410220090034"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70408-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(83)90970-5"},{"issue":"3","key":"e_1_2_8_6_1","first-page":"336","article-title":"A comparison of the ability of a sonographically measured biparietal diameter and the last menstrual period to predict the spontaneous onset of labor","volume":"76","author":"Waldenstrom U","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_7_1","first-page":"252","article-title":"Pharmacologic agents in the prevention of decompression sickness","volume":"11","author":"Campbell SD","year":"1969","journal-title":"J Occup Med"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4053"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2004.00485.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39129.637917.AE"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2006.01.010"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199812173392504"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1082"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00311.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb11111.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01678.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079006435.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079006440.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/17.4.830"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2009.06.007"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349009028712"},{"key":"e_1_2_8_22_1","first-page":"2314","article-title":"Routine ultrasonography in obstetric care in Norway, 1994","volume":"117","author":"Backe B","year":"1997","journal-title":"Tidsskr Nor Laegeforen"},{"key":"e_1_2_8_23_1","volume-title":"Graviditetskalenderen Snurra","author":"Eik\u2010Nes SH","year":"1983"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00691.x"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; 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