{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:41:15Z","timestamp":1787013675030,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T00:00:00Z","timestamp":1410912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek Vlaanderen","doi-asserted-by":"crossref","award":["1801207"],"award-info":[{"award-number":["1801207"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To report a recent update on fetuses with right\u2010sided congenital diaphragmatic hernia (\n                      <jats:styled-content style=\"fixed-case\">RCDH<\/jats:styled-content>\n                      ) in the era of fetal surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective review of prospectively collected data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Fetal treatment centres in Leuven and Barcelona.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>\n                      Consecutive cases of\n                      <jats:styled-content style=\"fixed-case\">RCDH<\/jats:styled-content>\n                      between 2002 and 2012.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data on prenatal imaging, genetic testing, pregnancy and neonatal outcomes were extracted from our databases, including structural and genetic anomalies, candidate outcome predictors such as lung size, liver herniation ratio, polyhydramnios, cervical length, preterm prelabour rupture of membranes and gestational age at birth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Survival and oxygen dependency at discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten out of 86 fetuses with\n                      <jats:styled-content style=\"fixed-case\">RCDH<\/jats:styled-content>\n                      had associated abnormalities. Of 76 isolated pregnancies, eight women opted for termination of pregnancy, most with severe hypoplasia and one was lost to follow up. Nineteen pregnancies were expectantly managed and delivered at a mean gestational age of 36.0\u00a0\u00b1\u00a03.0\u00a0weeks. Survival at discharge was 53% (10\/19), one being oxygen dependent. In the fetal surgery group (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a048), mean gestational age at delivery was 34.5\u00a0\u00b1\u00a03.0\u00a0weeks. In our recent experience not previously published (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a023) survival rate was 52 and 39% were oxygen dependent at discharge. Pooling these data with earlier reported observations by our group we observed a 42% survival rate in 57 fetuses. Lung size on magnetic resonance imaging and an interval of &gt;24\u00a0hours between reversal of tracheal occlusion and delivery were predictors of outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Right\u2010sided\n                      <jats:styled-content style=\"fixed-case\">CDH<\/jats:styled-content>\n                      seems to have a poorer outcome than that reported for fetuses with left\u2010sided\n                      <jats:styled-content style=\"fixed-case\">CDH<\/jats:styled-content>\n                      with similar lung size before birth. Survival rates after expectant management with observed\/expected lung\u2010to\u2010head ratio values \u226445 and \u226430% were 17 and 0%, respectively. In those undergoing fetal surgery (observed\/expected lung\u2010to\u2010head ratio \u226445%) there was an apparent increase (42%).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.13065","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T01:27:01Z","timestamp":1410917221000},"page":"940-946","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Right\u2010sided congenital diaphragmatic hernia in a decade of fetal surgery"],"prefix":"10.1111","volume":"122","author":[{"given":"P","family":"DeKoninck","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics and Gynaecology University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Gomez","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Department Institut Cl\u00ednic de Ginecologia Obstetr\u00edcia i Neonatologia (ICGON) Hospital Cl\u00ednic Institut d'Investigacions Biom\u00e9diques Augusto Pi i Sunyer (IDIBAPS) University of Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER) Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Sandaite","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics and Gynaecology University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"},{"name":"Department of Radiology University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Richter","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics and Gynaecology University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Nawapun","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics and Gynaecology University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Eerdekens","sequence":"additional","affiliation":[{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"},{"name":"Department of Paediatrics University Hospitals Leuven KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JC","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Department Institut Cl\u00ednic de Ginecologia Obstetr\u00edcia i Neonatologia (ICGON) Hospital Cl\u00ednic Institut d'Investigacions Biom\u00e9diques Augusto Pi i Sunyer (IDIBAPS) University of Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER) Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Claus","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospitals Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Gratacos","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Department Institut Cl\u00ednic de Ginecologia Obstetr\u00edcia i Neonatologia (ICGON) Hospital Cl\u00ednic Institut d'Investigacions Biom\u00e9diques Augusto Pi i Sunyer (IDIBAPS) University of Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER) Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Deprest","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics and Gynaecology University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"Department of Development and Regeneration Cluster Organ Systems KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.02.007"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/SLA.0b013e3181f5b538","article-title":"Impact of hospital volume on in\u2010hospital mortality of infants undergoing repair of congenital diaphragmatic hernia","volume":"252","author":"Bucher BT","year":"2010","journal-title":"Ann Surg"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2012.12.017"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.3.532"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.01.073"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2013.858691"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90338-3"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.04.004"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2442061158"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6139"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000320605"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2839"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2845"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12059"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31823886ee"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2000.8725"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.01.037"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2003.11.006"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3182192aa9"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4052"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6450"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000320622"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000320204"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-012-2709-6"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2651"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4244"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(94)90331-X"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2746"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2471070682"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7586"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-004-1226-3"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2522081955"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12414"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10142"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.13065","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.13065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T19:14:14Z","timestamp":1696274054000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.13065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,17]]},"references-count":34,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1111\/1471-0528.13065"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.13065","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,17]]},"assertion":[{"value":"2014-07-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}