{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:00:10Z","timestamp":1782396010680,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,2,25]],"date-time":"2015-02-25T00:00:00Z","timestamp":1424822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2015,9]]},"abstract":"Objective<\/jats:title>To evaluate the influence of chorionicity on outcome in twin pregnancies with two live fetuses at the nuchal translucency scan in the first trimester.<\/jats:p><\/jats:sec>Design<\/jats:title>Population\u2010based register study.<\/jats:p><\/jats:sec>Setting<\/jats:title>Denmark.<\/jats:p><\/jats:sec>Population<\/jats:title>A cohort of 3621 twin pregnancies, 84.3% dichorionic (DC<\/jats:styled-content>) pregnancies and 15.7% monochorionic (MC<\/jats:styled-content>) pregnancies (15% diamniotic [MCDA<\/jats:styled-content>] and 0.7% monoamniotic [MCMA<\/jats:styled-content>]).<\/jats:p><\/jats:sec>Methods<\/jats:title>A cohort study based on data collected from the Danish Fetal Medicine Database from July 2008 to July 2011.<\/jats:p><\/jats:sec>Main outcome measures<\/jats:title>Fetal loss rate before week 22, intrauterine death rate from week 22 to birth, and neonatal mortality.<\/jats:p><\/jats:sec>Results<\/jats:title>Significantly more DC<\/jats:styled-content> than MC<\/jats:styled-content> pregnancies resulted in at least one live born infant\u201498.2% versus 92.3% in MCDA<\/jats:styled-content> (P\u00a0<\/jats:italic><\u00a00.05) and 66.7% in MCMA<\/jats:styled-content> pregnancies (P\u00a0<\/jats:italic><\u00a00.05). The rates of spontaneous loss of both fetuses before week 22 were 0.9, 2.4, and 20.8% for DC<\/jats:styled-content>, MCDA<\/jats:styled-content> and MCMA<\/jats:styled-content> twins, respectively (P\u00a0<\/jats:italic><\u00a00.05). The rate of intrauterine death of one fetus after week 22 was higher in MCDA<\/jats:styled-content> twins than DC<\/jats:styled-content> twins 1.7% versus 0.6% (P\u00a0<\/jats:italic><\u00a00.05). We found no significant difference in the rate of neonatal death.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The risk of spontaneous loss of both fetuses before week 22 of gestation was significantly higher in MCMA<\/jats:styled-content> and MCDA<\/jats:styled-content> pregnancies than in DC<\/jats:styled-content> pregnancies, and significantly higher in MCMA<\/jats:styled-content> pregnancies than in MCDA<\/jats:styled-content> pregnancies. After week 22 the risk of loss of one fetus after week 22 was significantly higher in MCDA<\/jats:styled-content> pregnancies than in DC<\/jats:styled-content> pregnancies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.13326","type":"journal-article","created":{"date-parts":[[2015,2,25]],"date-time":"2015-02-25T19:56:48Z","timestamp":1424894208000},"page":"1362-1369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Perinatal outcome after first\u2010trimester risk assessment in monochorionic and dichorionic twin pregnancies: a population\u2010based register study"],"prefix":"10.1111","volume":"122","author":[{"given":"MK","family":"Kristiansen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital Skejby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BS","family":"Joensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital Skejby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CK","family":"Ekelund","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Department of Obstetrics Copenhagen University Hospital Rigshospitalet Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OB","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital Skejby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Sandager","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital Skejby Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"with the Danish Fetal Medicine Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.121721"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.01.024"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10057"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01556.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3820"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0965539503001074"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2009.05.001"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den104"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)85858-9"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01172.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a2547"},{"key":"e_1_2_7_13_1","unstructured":"MiltoftCB EkelundC TaborA.F\u00d8TODATABASEN annual report.2011."},{"key":"e_1_2_7_14_1","unstructured":"Statistics Denmark.Statistikbanken. 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