{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T17:57:19Z","timestamp":1770487039048,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T00:00:00Z","timestamp":1443571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Region Zealand Health research fund"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the 1\u2013year (previously published) and 3\u2013year objective and subjective cure rates, and complications, related to the use of a collagen\u2010coated transvaginal mesh for anterior vaginal wall prolapse against a conventional anterior repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Randomised controlled study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Six departments of obstetrics and gynaecology in Norway, Sweden, Finland, and Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A total of 138 women, of 55 years of age or older, admitted for stage \u22652 anterior vaginal wall prolapse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The women scheduled for primary anterior vaginal wall prolapse surgery were randomised between conventional anterior colporrhaphy and surgery with a collagen\u2010coated prolene mesh. All patients were evaluated using the Pelvic Organ Prolapse Quantification (<jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>\u2013Q) assessment before and after surgery. Symptoms related to pelvic organ prolapse were evaluated using the Pelvic Floor Impact Questionnaire (<jats:styled-content style=\"fixed-case\">PFIQ<\/jats:styled-content>\u20137) and the Pelvic Floor Distress Inventory (<jats:styled-content style=\"fixed-case\">PFDI<\/jats:styled-content>\u201320).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Objective cure, defined as <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>\u2013Q stage &lt;2 prolapse at the 1\u2010 and 3\u2013year follow\u2010ups. Furthermore, mesh exposure and dyspareunia were also recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 138 patients (70 from the mesh group versus 68 from the conventional anterior colporrhaphy group) out of 160 (86.3%) participated in the 3\u2013year follow\u2010up. <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>\u2013Q revealed an objective anatomic cure for 88.1 and 91.4%, respectively, in the mesh group at the 1\u2010 and 3\u2013year follow\u2010ups, compared with 39.9 and 41.2% in the colporrhaphy group. No difference between the groups was observed regarding <jats:styled-content style=\"fixed-case\">PFIQ<\/jats:styled-content>\u20137, <jats:styled-content style=\"fixed-case\">PFDI<\/jats:styled-content>\u201320, and Pelvic Organ Prolapse\/Urinary Incontinence Sexual Questionnaire (<jats:styled-content style=\"fixed-case\">PISQ<\/jats:styled-content>\u201312) scores. The number of mesh exposures did not change during the study period and all exposures were minor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study demonstrates that although the objective outcome was superior in the mesh group, the use of mesh had no impact on the subjective outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>\u2013Q deteriorates after anterior prolapse surgery but remains stable in women with mesh implantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.13628","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T09:09:59Z","timestamp":1443604199000},"page":"136-142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["A 3\u2013year follow\u2010up after anterior colporrhaphy compared with collagen\u2010coated transvaginal mesh for anterior vaginal wall prolapse: a randomised controlled trial"],"prefix":"10.1111","volume":"123","author":[{"given":"M","family":"Rudnicki","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Odense University Hospital Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Laurikainen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Turku University Hospital Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Pogosean","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Lidk\u00f6ping Hospital Lidk\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Kinne","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Ahus University Hospital Ahus Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Jakobsson","sequence":"additional","affiliation":[{"name":"Centre for Primary Healthcare Research Faculty of Medicine University of Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Teleman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Skane University Hospital University of Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00058-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.119081"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31816a2489"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02254.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.03.030"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318237edc4"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03082.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009521"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2344-7"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12454"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2501-z"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2511-x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004014.pub5"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.07.040"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-014-3316-3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12040"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.10.003"},{"key":"e_1_2_7_19_1","unstructured":"US Food and Drug Administration.FDA safety communication: Update on Serious Complications Associated with Transvaginal Placement of Surgical Mesh for Pelvic Organ Prolapse July 13 2011. 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