{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T10:26:37Z","timestamp":1768472797907,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T00:00:00Z","timestamp":1451347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To develop maternal, fetal, and neonatal composite outcomes relevant to the evaluation of diet and lifestyle interventions in pregnancy by individual patient data (<jats:styled-content style=\"fixed-case\">IPD<\/jats:styled-content>) meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Delphi survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The International Weight Management in Pregnancy (i\u2013<jats:styled-content style=\"fixed-case\">WIP<\/jats:styled-content>) collaborative network. Sample Twenty\u2010six researchers from the i\u2013<jats:styled-content style=\"fixed-case\">WIP<\/jats:styled-content> collaborative network from 11 countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A two\u2010generational Delphi survey involving members of the i\u2013<jats:styled-content style=\"fixed-case\">WIP<\/jats:styled-content> collaborative network (26 members in 11 countries) was undertaken to prioritise the individual outcomes for their importance in clinical care. The final components of the composite outcomes were identified using pre\u2010specified criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Composite outcomes considered to be important for the evaluation of the effect of diet and lifestyle in pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 36 maternal outcomes, nine were prioritised and the following were included in the final composite: pre\u2010eclampsia or pregnancy\u2010induced hypertension, gestational diabetes mellitus (<jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>), elective or emergency caesarean section, and preterm delivery. Of the 27 fetal and neonatal outcomes, nine were further evaluated, with the final composite consisting of intrauterine death, small for gestational age, large for gestational age, and admission to a neonatal intensive care unit (<jats:styled-content style=\"fixed-case\">NICU<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our work has identified the components of maternal, fetal, and neonatal composite outcomes required for the assessment of diet and lifestyle interventions in pregnancy by <jats:styled-content style=\"fixed-case\">IPD<\/jats:styled-content> meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Composite outcomes in IPD meta\u2010analysis on diet and lifestyle in pregnancy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.13764","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T07:28:53Z","timestamp":1451374133000},"page":"190-198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Development of composite outcomes for individual patient data (<scp>IPD<\/scp>) meta\u2010analysis on the effects of diet and lifestyle in pregnancy: a Delphi survey"],"prefix":"10.1111","volume":"123","author":[{"given":"E","family":"Rogozinska","sequence":"first","affiliation":[{"name":"Women's Health Research Unit Barts and the London School of Medicine and Dentistry Queen Mary University London London UK"},{"name":"Multidisciplinary Evidence Synthesis Hub (mEsh) Barts and the London School of Medicine and Dentistry Queen Mary University London London 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