{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:52:16Z","timestamp":1787237536256,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T00:00:00Z","timestamp":1450915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001732","name":"Danmarks Grundforskningsfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001732","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004954","name":"Augustinus Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004954","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000724","name":"Health Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000724","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate whether eating disorders are associated with lower size at birth, symmetric growth restriction, and preterm birth; and whether pregnancy smoking explains the association between anorexia nervosa and fetal growth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Longitudinal population\u2010based cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Denmark.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Sample<\/jats:title>\n                    <jats:p>\n                      Women from the Danish National Birth Cohort (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a083\u00a0826).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Women with anorexia nervosa (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01609), bulimia nervosa (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a01693) and both (anorexia + bulimia nervosa,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0634) were compared with unexposed women (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a076\u00a0724) (women with exposure data and singletons\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a080\u00a0660) using crude and adjusted linear and logistic regression models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>\n                      Size at birth (birthweight, length, head and abdominal circumference and placental weight); gestational age; small\u2010 and large\u2010for\u2010gestational\u2010age (\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">LGA<\/jats:styled-content>\n                      ); ponderal index, abdominal\/head circumference.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Lifetime anorexia nervosa and lifetime anorexia +\u00a0bulimia nervosa were prospectively associated with restricted fetal growth and higher odds of\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      [respectively,\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u00a0=\u00a01.6 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.3\u20131.8] and\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u00a0=\u00a01.5 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.2\u20131.9)] compared with unexposed women. Active anorexia nervosa was associated with lower birthweight, length, head and abdominal circumference, ponderal index, higher odds of\n                      <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>\n                      [\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u00a0=\u00a02.90 (95% 1.98\u20134.26)] and preterm birth [\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u00a0=\u00a01.77 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.00\u20133.12)] compared with\u00a0unexposed women. Pregnancy smoking only partly explained the association between anorexia nervosa and adverse fetal outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal anorexia nervosa (both active and past) is associated with lower size at birth and symmetric growth restriction, with evidence of worse outcomes in women with active disorder. Women with anorexia nervosa should be advised\u00a0about achieving full recovery before conceiving. Similarly,\u00a0targeting smoking in pregnancy might improve fetal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Tweetable abstract<\/jats:title>\n                    <jats:p>Anorexia nervosa predicts small size at birth, small\u2010for\u2010gestational\u2010age and symmetric growth restriction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.13825","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T06:52:00Z","timestamp":1450939920000},"page":"1301-1310","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Size at birth and preterm birth in women with lifetime eating disorders: a prospective population\u2010based study"],"prefix":"10.1111","volume":"123","author":[{"given":"N","family":"Micali","sequence":"first","affiliation":[{"name":"Behavioural and Brain Sciences Unit Institute of Child Health UCL London UK"},{"name":"Department of Psychiatry and Mindich Child Health and Development Institute Icahn Medical School at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Stemann Larsen","sequence":"additional","affiliation":[{"name":"Section\u00a0of Social Medicine Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Strandberg\u2010Larsen","sequence":"additional","affiliation":[{"name":"Section\u00a0of Social Medicine Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A\u2010M","family":"Nybo Andersen","sequence":"additional","affiliation":[{"name":"Section\u00a0of Social Medicine Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.10222"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2229"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2007.05.003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f7efdc"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxt004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.03.067"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12370"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7292.949"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0708473"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.65.9.1080"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.1374"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.106.020768"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/14034948010290040201"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03467.x"},{"key":"e_1_2_7_16_1","unstructured":"NohrE.Obesity in pregnancy: Epidemiological studies based on the Danish National Birth Cohort. 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