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Pregnancies with aneuploidy, structural or skeletal abnormalities, or that developed pre\u2010eclampsia were excluded. <jats:italic>Z<\/jats:italic>\u2010scores were stratified as &lt;2.5th, &lt;5th, &lt;10th, &gt;90th, &gt;95th, or &gt;97.5th percentile. Birthweight centile, adjusted for gestation and gender, was categorised as \u22643rd, 3rd to \u22645th, 5th to \u226410th, and &gt;10th. Pairwise comparison and the McNemar test were performed to assess biometry <jats:italic>Z<\/jats:italic>\u2010score differences and concordance between the <jats:styled-content style=\"fixed-case\">INTERGROWTH<\/jats:styled-content>\u201021<jats:sup>st<\/jats:sup> and Chinese standards.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The sensitivity of both the local and <jats:styled-content style=\"fixed-case\">INTERGROWTH<\/jats:styled-content>\u201021<jats:sup>st<\/jats:sup> <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> standards to identify pregnancies that were small\u2010for\u2010gestational\u2010age (SGA) was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">INTERGROWTH<\/jats:styled-content>\u201021<jats:sup>st<\/jats:sup> <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> HC<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">FL <\/jats:styled-content><jats:italic>Z<\/jats:italic>\u2010scores were significantly lower than those obtained using our local reference for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> HC<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001 for all). The proportion of fetuses with biometry in the &lt;2.5th, &lt;5th, &lt;10th, &gt;90th, &gt;95th, or &gt;97.5th percentiles was statistically significant (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01 for all). A total of 1224 (15.5%) of the scans at 18\u201322\u00a0weeks of gestation had <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> HC<\/jats:styled-content>, or <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> below the 3rd percentile of the <jats:styled-content style=\"fixed-case\">INTERGROWTH<\/jats:styled-content>\u201021<jats:sup>st<\/jats:sup> standard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Adopting the <jats:styled-content style=\"fixed-case\">INTERGROWTH<\/jats:styled-content>\u201021<jats:sup>st<\/jats:sup> standard would lead to a significant number of fetuses being at risk of misdiagnosis for small fetal size, particularly when using <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>INTERGROWTH\u201021<jats:sup>st<\/jats:sup> biometry assessment in Chinese leads to fetuses being at risk of misdiagnosis of small fetal size.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14008","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T15:05:30Z","timestamp":1473865530000},"page":"48-55","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Impact of replacing <scp>C<\/scp>hinese ethnicity\u2010specific fetal biometry charts with the <scp>INTERGROWTH<\/scp>\u201021<sup>st<\/sup> standard"],"prefix":"10.1111","volume":"123","author":[{"given":"YKY","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TY","family":"Leung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TTH","family":"Lao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YM","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DS","family":"Sahota","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,9,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61490-2"},{"key":"e_1_2_6_3_1","first-page":"312","volume-title":"WHO Child Growth Standards: Length\/Height\u2010for\u2010age, Weight\u2010for\u2010age, Weight\u2010for\u2010length, Weight\u2010for\u2010height and Body Mass Index\u2010for\u2010age: Methods and Development","author":"World Health Organisation (WHO)","year":"2006"},{"key":"e_1_2_6_4_1","volume-title":"WHO Child Growth Standards: Head Circumference\u2010for\u2010age, Arm Circumference\u2010for\u2010age, Triceps Skinfold\u2010for\u2010age and Subscapular Skinfold\u2010for\u2010age: Methods and Development","author":"World Health Organization","year":"2007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12047"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12125"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03451.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61416-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5265"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2319"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33251"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7172.1549"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70006-8"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5192"},{"key":"e_1_2_6_15_1","unstructured":"Census and Statistics Department Hong Kong Special Administrative Region.Population and Household Statistics Analysed by District Council Distrist 2013.www.statistics.gov.hk\/pub\/B11303012013AN13B0100.pdf. 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