{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:47:03Z","timestamp":1787838423320,"version":"build-2784847793"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,6,12]],"date-time":"2016-06-12T00:00:00Z","timestamp":1465689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Centre for Research & Development, Uppsala University\/County Council of G\u00e4vleborg, G\u00e4vle, Sweden"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether superior hypogastric plexus block performed during abdominal hysterectomy decreases postoperative opioid consumption and pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A randomised, double\u2010blind, placebo\u2010controlled, clinical trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>A county hospital in Sweden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Sixty\u2010eight women scheduled for total abdominal hysterectomy for a benign indication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u00a0ml of ropivacaine 7.5\u00a0mg\/ml or saline was injected retroperitoneally in the area of the superior hypogastric plexus during the hysterectomy. The participants were individually randomised to either intervention. The participants, caregivers, and those assessing the outcomes were blinded to group assignment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The primary outcomes were postoperative opiate consumption and patients\u2019 self\u2010assessment of pain (VAS scores). Secondary outcomes were mobilisation and side effects related to opiate consumption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The trial was completed with 38 women randomised to ropivacaine and 37 women randomised to saline. Analysis was performed on 35 women in the ropivaciane group and 33 women in the saline group. The postoperative opioid consumption was significantly lower in the ropivacaine group than in the placebo group (median 55.8 and 72.4\u00a0mg, respectively, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.032). The proportion of women scoring VAS &lt;4 at 2\u00a0hours after block was significantly higher in the ropivacaine group (63%) than in the placebo group (25%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.015). No side effects or important adverse events occurred during the trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The superior hypogastric plexus block is a new method in this context and a promising contribution to postoperative pain treatment after abdominal hysterectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Superior hypogastric plexus block during abdominal hysterectomy lowers opioid consumption.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14119","type":"journal-article","created":{"date-parts":[[2016,6,13]],"date-time":"2016-06-13T02:05:13Z","timestamp":1465783513000},"page":"270-276","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Superior hypogastric plexus block as a new method of pain relief after abdominal hysterectomy: double\u2010blind, randomised clinical trial of efficacy"],"prefix":"10.1111","volume":"124","author":[{"given":"H","family":"Rapp","sequence":"first","affiliation":[{"name":"Department of Gynaecology and Obstetrics G\u00e4vle Hospital G\u00e4vle Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Ledin Eriksson","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology G\u00e4vle Hospital G\u00e4vle Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics G\u00e4vle Hospital G\u00e4vle Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-008-0615-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.05.010"},{"issue":"3","key":"e_1_2_6_4_1","first-page":"CD005428","article-title":"Surgical approach to hysterectomy for benign gynaecological disease","author":"Nieboer TE","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199204000-00007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.1998.00635.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bja.a013412"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0002800504"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/81.3.377"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0004-8666.2002.00515.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000130260.24433.A2"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00115550-199924060-00018"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000255706.11417.9b"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182334d8b"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181871313"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2010.04.001"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02697.x"},{"key":"e_1_2_6_18_1","first-page":"102","article-title":"Le traitment de la nevralgie pelviene par la paralysie du sympathique sacre","volume":"90","author":"Jaboulay M","year":"1899","journal-title":"Lyon Med"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199008000-00008"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-70942005000600011"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ajp.0000202978.06045.24"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1177\/0310057X0803600518","article-title":"Anterior ultrasound\u2010guided superior hypogastric plexus neurolysis in pelvic cancer pain","volume":"36","author":"Mishra S","year":"2008","journal-title":"Anaesth Intensive Care"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00291.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2011.00467.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/AJP.0b013e3181dedfa9","article-title":"Evaluation of posteromedial transdiscal superior hypogastric block after failure of the classic approach","volume":"26","author":"Nabil D","year":"2010","journal-title":"Clin J Pain"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.04.023"},{"key":"e_1_2_6_27_1","unstructured":"R Development Core Team R: A Language and Environment for Statistical Computing.Vienna Austria:R Foundation for Statistical Computing;2006. 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