{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:05:09Z","timestamp":1790157909412,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T00:00:00Z","timestamp":1469577600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009406","name":"Nantes University Hospital (France)","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009406","id-type":"DOI","asserted-by":"crossref"}]},{"name":"French Ministry of Health (Paris)"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,1]]},"abstract":"\n Objective<\/jats:title>\n To compare the effect of corticosteroids combined with local anaesthetic versus local anaesthetic alone during infiltrations of the pudendal nerve for pudendal nerve entrapment.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Randomised, double\u2010blind, controlled trial.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Multicentre study.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n 201 patients were included in the study, with a subgroup of 122 women.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n CT<\/jats:styled-content>\n \u2010guided pudendal nerve infiltrations were performed in the sacrospinous ligament and Alcock's canal. There were three study arms: patients in Arm A (\n n<\/jats:italic>\n \u00a0=\u00a068) had local anaesthetic alone, those in Arm B (\n n\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 66) had local anaesthetic plus corticosteroid and those in Arm C (\n n\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 67) local anaesthetic plus corticosteroid with a large volume of normal saline.\n <\/jats:p>\n <\/jats:sec>\n \n Main outcome measures<\/jats:title>\n The primary end\u2010point was the pain intensity score at 3\u00a0months. Patients were regarded as responders (at least a 30\u2010point improvement on a 100\u2010point visual analogue scale of mean maximum pain over a 2\u2010week period) or nonresponders.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Three months\u2019 postinfiltration, 11.8% of patients in the\u00a0local anaesthetic only arm (Arm A) were responders versus 14.3% in the local anaesthetic plus corticosteroid arms (Arms B and C). This difference was not statistically significant (\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.62). No statistically significant difference was observed in the female\u00a0subgroup between Arm A and Arms B and C (\n P\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.09). No significant difference was detected for the various pain assessment procedures, functional criteria or quality\u2010of\u2010life criteria.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Corticosteroids provide no additional therapeutic benefits compared with local anaesthetic and should therefore no longer be used.<\/jats:p>\n <\/jats:sec>\n \n Tweetable abstract<\/jats:title>\n Steroid infiltrations do not improve the results of local anaesthetic infiltrations in pudendal neuralgia.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1471-0528.14222","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T22:18:43Z","timestamp":1469657923000},"page":"251-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Adding corticosteroids to the pudendal nerve block for pudendal neuralgia: a randomised, double\u2010blind, controlled trial"],"prefix":"10.1111","volume":"124","author":[{"given":"JJ","family":"Labat","sequence":"first","affiliation":[{"name":"Federative Centre of Pelvi\u2010Perineology CHU Nantes Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Riant","sequence":"additional","affiliation":[{"name":"Federative Centre of Pelvi\u2010Perineology CHU Nantes Nantes France"},{"name":"Pain Unit Centre Catherine de Sienne Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Lassaux","sequence":"additional","affiliation":[{"name":"Pain Clinic H\u00f4pital Rothschild Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Rioult","sequence":"additional","affiliation":[{"name":"Pain Unit Centre Catherine de Sienne Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Rabischong","sequence":"additional","affiliation":[{"name":"Gynaecology Department Polyclinique H\u00f4tel\u2010Dieu Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Khalfallah","sequence":"additional","affiliation":[{"name":"Centre Hospitalier de la Cote Basque Bayonne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Volteau","sequence":"additional","affiliation":[{"name":"DRCI H\u00f4tel Dieu Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A\u2010M","family":"Leroi","sequence":"additional","affiliation":[{"name":"Digestive Physiology Department H\u00f4pital Charles Nicolle Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Ploteau","sequence":"additional","affiliation":[{"name":"Federative Centre of Pelvi\u2010Perineology CHU Nantes Nantes France"},{"name":"Gynaecology Department H\u00f4tel\u2010Dieu Nantes 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