{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:24:34Z","timestamp":1761513874221},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,9,5]],"date-time":"2016-09-05T00:00:00Z","timestamp":1473033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NeuroDevNet Network of Centres of Excellence (NDN-NCE)"},{"name":"R\u00e9seau de recherche sur le d\u00e9veloppement, la sant\u00e9 et le bien-\u00eatre de l'enfant (RSDE) des Fonds de Recherche en Sant\u00e9 du Qu\u00e9bec (FRSQ)"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether cerebral palsy (CP) risks factors, neurological subtype, severity and co\u2010morbidities differ between early\/full\u2010term\u2010born children with CP compared with those born late\/post\u2010term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Children with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> born between 1998 and 2014, residing in Canada, and registered in the Canadian Cerebral Palsy Registry (<jats:styled-content style=\"fixed-case\">CCPR<\/jats:styled-content>) (<jats:italic>n<\/jats:italic> = 1691), a database with information from 15 participating centres across six Canadian provinces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Children with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> from the <jats:styled-content style=\"fixed-case\">CCPR<\/jats:styled-content> born at 37 weeks of gestation and later (<jats:italic>n<\/jats:italic> = 802).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical profile of children with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> born at 37\u201340 weeks of gestation was compared with those born at 41 weeks and later using the Pearson chi\u2010square test (or Fisher's exact test) for univariate analyses of categorical data. A <jats:italic>P<\/jats:italic> value &lt;0.05 was considered significant a priori.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> neurological subtype, Gross Motor Function Classification System (<jats:styled-content style=\"fixed-case\">GMFCS<\/jats:styled-content>) severity, risk factors and co\u2010morbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Neonatal encephalopathy was found in 23.9% of children with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> born early\/full\u2010term and in 33.6% of those born late\/post\u2010term (<jats:italic>P<\/jats:italic> = 0.026). Neonatal hyperbilirubinaemia was found in 10.2% of children born in the earlier period and in 2.6% of those born in the later period (<jats:italic>P<\/jats:italic> = 0.008). Apgar score at 5 minutes, but not 10 minutes, was significantly higher in the early\/full\u2010term group (9) compared with its late\/post\u2010term counterpart (7; <jats:italic>P<\/jats:italic> = 0.046). Rates of <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> subtype, severity (<jats:styled-content style=\"fixed-case\">GMFCS<\/jats:styled-content>) and co\u2010morbidities did not differ significantly between the two gestational periods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In children with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content>, neonatal encephalopathy was significantly less frequent and neonatal hyperbilirubinaemia was significantly more frequent in those born early\/full\u2010term compared with their later\u2010born counterparts. However, clinical outcomes of <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> were not significantly different between these two gestational epochs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Children with cerebral palsy born early\/full\u2010term have similar outcomes to those born late\/post\u2010term.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14240","type":"journal-article","created":{"date-parts":[[2016,9,5]],"date-time":"2016-09-05T07:07:07Z","timestamp":1473059227000},"page":"1738-1745","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Clinical profile of children with cerebral palsy born term compared with late\u2010 and post\u2010term: a retrospective cohort study"],"prefix":"10.1111","volume":"124","author":[{"given":"R","family":"Frank","sequence":"first","affiliation":[{"name":"Faculty of Medicine McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Garfinkle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine, McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Oskoui","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine, McGill University Montreal Quebec Canada"},{"name":"Department of Neurology &amp; Neurosurgery Faculty of Medicine, McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MI","family":"Shevell","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Faculty of Medicine, McGill University Montreal Quebec Canada"},{"name":"Department of Neurology &amp; Neurosurgery Faculty of Medicine, McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199401203300308"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8949"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0945"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2011.01217.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12017"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12080"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1271"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437385.88715.4a"},{"key":"e_1_2_6_10_1","unstructured":"MartinJA HamiltonBE OstermanMJK CurtinSC MathewsTJ.Births: Final data for 2013. National vital statistics reports [Internet]2015;64. [www.cdc.gov\/nchs\/data\/nvsr\/nvsr64\/nvsr64_01.pdf]. Accessed 25 November 2015"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102015\u2010308553"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.02.035"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2014.12.005"},{"key":"e_1_2_6_14_1","first-page":"8","article-title":"A report: the definition and classification of cerebral palsy April 2006","volume":"109","author":"Rosenbaum P","year":"2007","journal-title":"Dev Med Child Neurol Suppl"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1997.tb07414.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2000.tb00093.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181aa537b"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-9091(98)80020-X"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2009.12.004"},{"key":"e_1_2_6_20_1","first-page":"181","article-title":"The Bhutani nomogram reduces incidence of severe hyperbilirubinaemia in term and near term infants","volume":"108","author":"O'Reilly P","year":"2015","journal-title":"Ir Med J"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2010.05.010"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(01)00496-9"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00542-5"},{"key":"e_1_2_6_24_1","article-title":"Timing of delivery and pregnancy outcomes in women with gestational diabetes","author":"Feghali MN","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31822ad2dc"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000247174.27979.6b"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)32945-0"},{"key":"e_1_2_6_28_1","volume-title":"Caesarean Section","author":"National Collaborating Centre for Women's and Children's Health (UK)","year":"2011"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000428647.67925.d3"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgyn.2011.09.007"},{"key":"e_1_2_6_31_1","first-page":"175","article-title":"Postterm pregnancy","volume":"4","author":"Galal M","year":"2012","journal-title":"Facts Views Vis Obgyn"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01370-9"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.14240","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.14240","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.14240","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T02:08:00Z","timestamp":1694311680000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.14240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,5]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/1471-0528.14240"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.14240","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,5]]},"assertion":[{"value":"2016-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}