{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T14:48:28Z","timestamp":1785941308283,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T00:00:00Z","timestamp":1487894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000325","name":"Wellbeing of Women","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the incidence, risks, management and outcomes of cardiac arrest in pregnancy in the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> population, with specific focus on the use of perimortem caesarean section (<jats:styled-content style=\"fixed-case\">PMCS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A prospective, descriptive study using the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> Obstetric Surveillance System (<jats:styled-content style=\"fixed-case\">UKOSS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>All <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> hospitals with maternity units.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>All women who received basic life support in pregnancy in the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> between 1 July 2011 and 30 June 2014 (<jats:italic>n<\/jats:italic> = 66).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective case identification through <jats:styled-content style=\"fixed-case\">UKOSS<\/jats:styled-content> monthly mailing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Cardiac arrest in pregnancy, <jats:styled-content style=\"fixed-case\">PMCS<\/jats:styled-content>, maternal death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 66 cardiac arrests in pregnancy, resulting in an incidence of 2.78 per 100 000 maternities (1:36 000; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.2\u20133.6). In all, 28 women died (case fatality rate 42%); 16 women arrested solely as a consequence of obstetric anaesthesia, 12 of whom were obese. Basic and advanced life support were rapidly delivered. Those who died were more likely to have collapsed at home. Perimortem caesarean section was performed in 49 women, 11 in the emergency department. The time from collapse to <jats:styled-content style=\"fixed-case\">PMCS<\/jats:styled-content> was significantly shorter in women who survived (median interval 3 versus 12 minutes, <jats:italic>P<\/jats:italic> = 0.001). Forty\u2010six of 58 babies were born alive; 32 babies to surviving mothers and 14 to women who died.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cardiac arrest is rare in the pregnant <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> population, however, nearly a quarter of cases are precipitated by obstetric anaesthesia, suggesting an opportunity to reduce the incidence further. Maternal survival rates of 58% were achieved with timely resuscitation, including <jats:styled-content style=\"fixed-case\">PMCS<\/jats:styled-content>, delay in which was associated with maternal death. Inpatient arrests were associated with higher survival rates than arrests that occurred outside the hospital setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>25% of cardiac arrest in pregnancy is caused by anaesthesia. Rapid perimortem section improves survival.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14521","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T05:02:42Z","timestamp":1487912562000},"page":"1374-1381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":188,"title":["The <scp>CAPS<\/scp> Study: incidence, management and outcomes of cardiac arrest in pregnancy in the <scp>UK<\/scp>: a prospective, descriptive study"],"prefix":"10.1111","volume":"124","author":[{"given":"VA","family":"Beckett","sequence":"first","affiliation":[{"name":"Bradford Teaching Hospitals NHS Foundation Trust Bradford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Knight","sequence":"additional","affiliation":[{"name":"National Perinatal Epidemiology Unit University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Sharpe","sequence":"additional","affiliation":[{"name":"University Hospitals of Leicester NHS Trust Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7426.1277"},{"key":"e_1_2_6_3_1","unstructured":"G Lewis"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02461.x"},{"key":"e_1_2_6_5_1","first-page":"571","article-title":"Perimortem caesarean delivery","volume":"68","author":"Katz VL","year":"1986","journal-title":"Obstet Gynecol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781107445161"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.02.038"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000159"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00609.x"},{"key":"e_1_2_6_10_1","unstructured":"G Perkins M Colquhoun C Deakin A Handley C Smith M Smyth"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen360"},{"key":"e_1_2_6_12_1","volume-title":"Saving Lives, Improving Mothers\u2019 Care \u2013 Lessons learned to inform future maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2009\u20132012","author":"Knight M","year":"2014"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000171"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2008.01.015"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2007.10.002"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2008.07.008"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.07.017"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000264"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.14521","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.14521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:39:52Z","timestamp":1696293592000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.14521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,24]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/1471-0528.14521"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.14521","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,24]]},"assertion":[{"value":"2016-12-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}