{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T20:36:18Z","timestamp":1773866178589,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T00:00:00Z","timestamp":1493683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005003","name":"Baskent \u00dcniversitesi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare follicle flushing three times with direct follicular aspiration in poor responders. Our hypothesis was that follicle flushing three times in poor responders would result in similar oocyte yield compared with direct aspiration in poor responders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A randomised controlled trial performed between January 2015 and June 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population or sample<\/jats:title><jats:p>Eighty eligible poor responders, who were defined as having five or fewer follicles \u226513\u00a0mm in average diameter with at least two follicles having maximum diameters &gt;17\u00a0mm on the day of human chorionic gonadotrophin administration. Monofollicular cycles, including natural cycles, were excluded from the current trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In the double\u2010lumen needle group, oocyte retrieval was performed by flushing three times with 2\u00a0ml in each follicle and in the single\u2010lumen group direct follicle aspiration was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>Number of metaphase <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> oocytes retrieved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean number of metaphase <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> oocytes was similar in both groups (1.9\u00a0\u00b1\u00a00.1 versus 2.1\u00a0\u00b1\u00a00.1, respectively). The clinical pregnancy and live birth rates were similar in both groups (32.5% versus 25% and 25% versus 22.5%, respectively). The only significant difference between the two groups was the duration of oocyte retrieval (178.4\u00a0\u00b1\u00a013.4 versus 236.3\u00a0\u00b1\u00a024.1\u00a0seconds, respectively, <jats:italic>P\u00a0<\/jats:italic>=\u00a00.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Follicular flushing is time consuming and has similar results compared with direct follicle aspiration in poor responders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Direct follicle aspiration versus flushing in poor responders yields similar metaphase <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> oocytes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14629","type":"journal-article","created":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T03:20:13Z","timestamp":1489029613000},"page":"1190-1196","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["RETRACTED: Direct aspiration versus follicular flushing in poor responders undergoing intracytoplasmic sperm injection: a randomised controlled trial"],"prefix":"10.1111","volume":"124","author":[{"given":"B","family":"Haydardedeoglu","sequence":"first","affiliation":[{"name":"Division of Reproductive Endocrinology and IVF Unit Department of Obstetrics and Gynaecology Faculty of Medicine Baskent University Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Gjemalaj","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and IVF Unit Department of Obstetrics and Gynaecology Faculty of Medicine Baskent University Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PC","family":"Aytac","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and IVF Unit Department of Obstetrics and Gynaecology Faculty of Medicine Baskent University Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EB","family":"Kilicdag","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and IVF Unit Department of Obstetrics and Gynaecology Faculty of Medicine Baskent University Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2001.tb01212.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des174"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-012-9869-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.09.013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01130734"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)55230-3"},{"key":"e_1_2_6_8_1","first-page":"CD004634","article-title":"Follicular flushing during oocyte retrieval in assisted reproductive techniques","volume":"9","author":"Wongtra\u2010Ngan S","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-013-0006-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det350"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.2.313"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2009.04.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr029"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000434750"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13366"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14884"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14763"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-013-0124-9"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12054"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.65.1083"}],"updated-by":[{"DOI":"10.1111\/1471-0528.18319","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000}}],"container-title":["BJOG: An International Journal of Obstetrics &amp; 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