{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:11:43Z","timestamp":1782439903698,"version":"3.54.5"},"reference-count":11,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T00:00:00Z","timestamp":1504051200000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the clinical efficacies of high\u2010intensity focused ultrasound (<jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content>) and laparoscopic myomectomy (<jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content>) in the treatment of uterine fibroids and their effects on patients\u2019 quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A non\u2010randomised control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Gynaecological department in a university teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Patients with uterine fibroids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From November 2014 to November 2015, 166 patients with uterine fibroids were enrolled and underwent <jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a099) and <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a067) surgeries, respectively. Clinical efficacy, postoperative complications and quality of life after treatment were evaluated using the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 Scale to compare the differences in each variable at the 1\u2010year follow up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcomes measures<\/jats:title><jats:p>Differences in efficacy, safety and quality of life between the patients treated with <jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 12\u2010month follow\u2010up results showed that the <jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content> group had a total effective rate of 99%; only one patient underwent alternative treatment due to non\u2010apparent tumour shrinkage. All patients in the <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content> group showed complete tumour disappearance. Of these patients, 52 showed significant clinical improvement, 15 with partial clinical improvement, a total effective rate of 98%. There was no significant difference in effectivity rate between the two groups (<jats:italic>P\u00a0<\/jats:italic>&gt;\u00a00.05). Both treatments effectively improved patients\u2019 quality of life. Compared with the <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content> group, patients in the <jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content> group experienced no blood loss, a shorter hospital stay and fewer adverse effects and complications, the difference being statistically significant (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High\u2010intensity focused ultrasound can be as efficacious as <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content> therapy and effectively improve patients\u2019 quality of life in the treatment of uterine fibroids, with fewer adverse effects and complications, shorter hospital stays, and quicker postoperative recovery compared with <jats:styled-content style=\"fixed-case\">LM<\/jats:styled-content> therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Patients with uterine fibroids can be effectively treated with both <jats:styled-content style=\"fixed-case\">HIFU<\/jats:styled-content> and myomectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.14745","type":"journal-article","created":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T22:33:52Z","timestamp":1504305232000},"page":"36-39","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["High\u2010intensity focused ultrasound and laparoscopic myomectomy in the treatment of uterine fibroids: a comparative study"],"prefix":"10.1111","volume":"124","author":[{"given":"Y","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology the Fifth Affiliated Hospital of Xinjiang Medical University Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Ran","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology the Fifth Affiliated Hospital of Xinjiang Medical University Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology the Fifth Affiliated Hospital of Xinjiang Medical University Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology the Fifth Affiliated Hospital of Xinjiang Medical University Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology the Fifth Affiliated Hospital of Xinjiang Medical University Xinjiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.99"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1990.tb01804.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.113-a740"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000275283.39475.f6"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2842"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200207000-00003"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000090628"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-010-9909-8"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000729"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7455"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2262-8"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.14745","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.14745","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T07:59:24Z","timestamp":1694591964000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.14745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":11,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/1471-0528.14745"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.14745","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"2017-05-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}