{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:30:40Z","timestamp":1791653440411,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005111","name":"Rigshospitalet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007405","name":"Hjerteforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007405","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the subsequent reproductive outcome for a Danish nationwide cohort of women with peripartum cardiomyopathy (<jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Nationwide historic cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Secondary and tertiary centres across Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sample<\/jats:title><jats:p>Women with <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010one women with <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content> during 2005\u20132014 were identified in a nationwide, registry\u2010based study and the diagnosis was validated through audit of patient records. A new search for subsequent reproductive outcome in this cohort from 2005\u20132016 was conducted in the Danish National Birth Registry and the Danish National Patient Registry. Detailed clinical data were obtained from patient records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Sterilisations and subsequent reproductive outcomes after <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>, including all pregnancies, miscarriages, terminations and deliveries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 61 women with <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>, 13 (21%) had a total of 16 subsequent pregnancies resulting in one miscarriage, seven early terminations, one ectopic pregnancy and seven liveborn children. There were no maternal deaths or significant cardiac events during pregnancy, but one woman, who gave birth to a liveborn child, had a relapse of <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content> 7 weeks postpartum. None of the six women who had a first trimester termination, experienced relapse of <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>. Of the 13 women with a subsequent pregnancy, 62% had prior to this been advised against a new pregnancy due to the risk of recurrent <jats:styled-content style=\"fixed-case\">PPCM<\/jats:styled-content>. A total of four women (6.6%) were sterilised.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Peripartum cardiomyopathy affects women's reproduction with few subsequent pregnancies resulting in a liveborn child. The finding of a 1\/7 relapse among women with recovered <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content> is in accordance with most previous studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Outcome in pregnancies after peripartum cardiomyopathy: results from the first nationwide study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.15046","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T16:16:48Z","timestamp":1512577008000},"page":"1018-1025","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Subsequent reproductive outcome among women with peripartum cardiomyopathy: a nationwide study"],"prefix":"10.1111","volume":"125","author":[{"given":"M","family":"Guldbrandt Hauge","sequence":"first","affiliation":[{"name":"Department of Obstetrics Copenhagen University Hospital Rigshospitalet 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