{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:03:27Z","timestamp":1793070207011,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T00:00:00Z","timestamp":1537142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the association between the residual cervix measured on postoperative <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> after radical vaginal trachelectomy (<jats:styled-content style=\"fixed-case\">RVT<\/jats:styled-content>) and adverse obstetrical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Referral Cancer centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Women who conceived after <jats:styled-content style=\"fixed-case\">RVT<\/jats:styled-content> for cervical cancer at the Royal Marsden Hospital, London, between 1995 and 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Postoperative <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scans were analysed by three researchers. The agreement between researchers was assessed by Pearson's correlation coefficient and Bland\u2013Altman plot. Patients were divided into two groups (&lt;10 and \u226510 mm residual cervix) for the analysis of adverse obstetrical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Late miscarriage, premature delivery, premature rupture of membranes (<jats:styled-content style=\"fixed-case\">PROM<\/jats:styled-content>) and chorioamnionitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scans were available; 29 of these women had a pregnancy that progressed beyond the first trimester. There was a strong reproducibility of the measurement of residual cervix (<jats:italic>P<\/jats:italic> &lt; 0.001). Nineteen women (65.5%) had &lt;10 mm residual cervix and 10 (34.5%) had \u226510 mm. Among women with &lt;10 mm residual cervix, seven (36.8%) experienced <jats:styled-content style=\"fixed-case\">PROM<\/jats:styled-content> and ten (66.7%) had a preterm birth; No women with \u226510 mm residual cervix had <jats:styled-content style=\"fixed-case\">PROM<\/jats:styled-content> and two (22.2%) had a preterm birth (<jats:italic>P<\/jats:italic> = 0.028 and <jats:italic>P<\/jats:italic> = 0.035, respectively). Overall, there were nine (16.7%) first\u2010trimester miscarriages, six (11.1%) late fetal losses, 12 (31.6%) preterm births and 36 (66.7%) live births. After a mean follow up of 78.1 months, 36 women were disease\u2010free and one woman had died.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> measurements of the residual cervix are reproducible between observers. The incidence of <jats:styled-content style=\"fixed-case\">PROM<\/jats:styled-content> and premature delivery is higher when the residual cervix after <jats:styled-content style=\"fixed-case\">RVT<\/jats:styled-content> is &lt;10 mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>The risk of prematurity after <jats:styled-content style=\"fixed-case\">RVT<\/jats:styled-content> can be predicted from measurements of residual cervical length on postoperative <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> scan.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.15429","type":"journal-article","created":{"date-parts":[[2018,8,12]],"date-time":"2018-08-12T12:14:51Z","timestamp":1534076091000},"page":"1726-1733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["<scp>MRI<\/scp> measurement of residual cervical length after radical trachelectomy for cervical cancer and the risk of adverse pregnancy outcomes: a blinded imaging analysis"],"prefix":"10.1111","volume":"125","author":[{"given":"RM","family":"Alvarez","sequence":"first","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"},{"name":"Department of Gynaecology and Gynaecological Oncology Santa Cristina University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Biliatis","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Rockall","sequence":"additional","affiliation":[{"name":"Department of Radiology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Papadakou","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SA","family":"Sohaib","sequence":"additional","affiliation":[{"name":"Department of Radiology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NM","family":"deSouza","sequence":"additional","affiliation":[{"name":"Department of Radiology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Butler","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Nobbenhuis","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DJP","family":"Barton","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"},{"name":"St George's University of London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JH","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TEJ","family":"Ind","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology The Royal Marsden Hospital NHS Trust London UK"},{"name":"St George's University of London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,9,17]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"FerlayJ SoerjomataramI ErvikM DikshitR EserS MathersC et al.Globocan 2012 v1.0 Cancer incidence and mortality worldwide. 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