{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:23:25Z","timestamp":1787235805955,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T00:00:00Z","timestamp":1556755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Robot\u2010assisted surgery is a recognised treatment for pelvic\u2010organ prolapse. Many of the surgical subgroup outcomes for apical prolapse are reported together, leading to a paucity of homogenous data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      Prospective observational cohort study (\n                      <jats:styled-content style=\"fixed-case\">NCT<\/jats:styled-content>\n                      01598467,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link>\n                      ) assessing outcomes for homogeneous subgroups of robot\u2010assisted apical prolapse surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Two European tertiary referral hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>\n                      Consecutive patients undergoing robot\u2010assisted sacrocolpopexy (\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      ) and supracervical hysterectomy with sacrocervicopexy (\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Anatomical cure (simplified Pelvic Organ Prolapse Quantification,\n                      <jats:styled-content style=\"fixed-case\">sPOPQ<\/jats:styled-content>\n                      , stage\u00a01), subjective cure (symptoms of bulge), and quality of life (Pelvic Floor Impact Questionnaire,\n                      <jats:styled-content style=\"fixed-case\">PFIQ<\/jats:styled-content>\n                      \u20107).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Primary outcome: anatomical and subjective cure. Secondary outcomes: surgical safety and intraoperative variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 305 patients were included (\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0188;\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0117). Twelve months follow\u2010up was available for 144 (\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      76.6%) and 109 (\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      93.2%) women. Anatomical success of the apical compartment occurred for 91% (\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      ) and in 99% (\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      ) of the women. In all compartments, the success percentages were 67 and 65%, respectively. Most recurrences were in the anterior compartment [15.7%\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      (symptomatic 12.1%); 22.9%\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      (symptomatic 4.8%)]. Symptoms of bulge improved from 97.4 to 17.4% (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005).\n                      <jats:styled-content style=\"fixed-case\">PFIQ<\/jats:styled-content>\n                      \u20107 scores improved from 76.7\u00a0\u00b1\u00a062.3 to 13.5\u00a0\u00b1\u00a031.1 (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005). The duration of surgery increased significantly for\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      [183.1\u00a0\u00b1\u00a038.2 versus 145.3\u00a0\u00b1\u00a029.8 (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005)]. Intraoperative complications and conversion rates were low (\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      , 5.3 and 4.3%;\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      , 0.0 and 0.0%). Four severe postoperative complications occurred after\n                      <jats:styled-content style=\"fixed-case\">RASC<\/jats:styled-content>\n                      (2.1%) and one occurred after\n                      <jats:styled-content style=\"fixed-case\">RSHS<\/jats:styled-content>\n                      (1.6%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the largest reported prospective cohort study on robot\u2010assisted apical prolapse surgery. Both procedures are safe, with durable results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Tweetable abstract<\/jats:title>\n                    <jats:p>European bi\u2010centre trial concludes that robot\u2010assisted surgery is a viable approach to managing apical prolapse.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.15696","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T05:52:01Z","timestamp":1553838721000},"page":"1065-1073","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Robot\u2010assisted surgery for the management of apical prolapse: a bi\u2010centre prospective cohort study"],"prefix":"10.1111","volume":"126","author":[{"given":"F","family":"van Zanten","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Meander Medical Centre Amersfoort the 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