{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:45:40Z","timestamp":1792633540825,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The present study aimed to analyse the Korean National Health Insurance Service (<jats:styled-content style=\"fixed-case\">NHIS<\/jats:styled-content>) cohort data to examine the safety of acupuncture therapy during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Korea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population or sample<\/jats:title><jats:p>Women with confirmed pregnancy between 2003 and 2012 from the 2002\u201313 <jats:styled-content style=\"fixed-case\">NHIS<\/jats:styled-content> sample cohort (<jats:italic>n<\/jats:italic>\u00a0=\u00a020\u00a0799).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women with confirmed pregnancy were identified and divided into acupuncture or control group for comparison of their outcomes. Differences in other factors such as age, and rate of high\u2010risk pregnancy and multiple pregnancy were examined. In the acupuncture group, the most frequent acupuncture diagnosis codes and the timing of treatment were also investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Incidence of full\u2010term delivery, preterm delivery and stillbirth by pregnancy duration and among the high\u2010risk and multiple pregnancy groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 20\u00a0799 pregnant women analysed, 1030 (4.95%) and 19\u00a0749 were in the acupuncture and control groups, respectively. Both overall (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] 1.23; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.98\u20131.54), and in the stratified analysis of high\u2010risk pregnancies (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.09; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.73\u20131.64), there was no significant difference between acupuncture and control groups in preterm deliveries. No stillbirths occurred in the acupuncture group and 0.035% of pregnancies resulted in stillbirths in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No significant difference in delivery outcomes (preterm delivery and stillbirth) was observed between confirmed pregnancies in the acupuncture and control groups. Therefore, in pregnancy, acupuncture therapy may be a safe therapeutic modality for relieving discomfort without an adverse delivery outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>In pregnancy, acupuncture therapy may be a safe therapeutic modality for relieving discomfort without an adverse outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.15925","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T16:19:38Z","timestamp":1567613978000},"page":"79-86","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Safety of acupuncture during pregnancy: a retrospective cohort study in Korea"],"prefix":"10.1111","volume":"127","author":[{"given":"H\u2010Y","family":"Moon","sequence":"first","affiliation":[{"name":"Jaseng Hospital of Korean Medicine Seoul 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