{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:33:35Z","timestamp":1791380015889,"version":"4.3.3"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,2,14]],"date-time":"2020-02-14T00:00:00Z","timestamp":1581638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the intrauterine fetal growth pattern and fetoplacental circulation in pregnancies following bariatric surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Maternity Unit, UK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>One hundred and sixty\u2010two pregnant women; 54 with previous bariatric surgery and 108 with no surgery but similar booking body mass index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were seen at 11\u201314, 20\u201324, 30\u201333 and 35\u201337\u00a0weeks of gestation and an oral glucose tolerance test (OGTT) was performed at 27\u201330\u00a0weeks. Fetal head and abdominal circumference (AC), femur length (FL), estimated fetal weight (EFW) and fetoplacental Dopplers were measured at three time\u2010points in pregnancy. Birthweight (BW) was recorded. Variables were modelled after adjustment for maternal\/pregnancy characteristics. Model estimates are reported as posterior means and quantile\u2010based 90% credible intervals (CrI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Fetal biometry, fetoplacental Doppler, BW.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with the no surgery group, the post\u2010bariatric surgery group had lower EFW during gestation (up to \u2212120\u00a0g; [\u2212189\u00a0g, \u221251\u00a0g] lighter) at 35\u201337\u00a0weeks, with smaller AC and FL. Similarly, infants of mothers with previous bariatric surgery had lower average BW [\u2212202\u00a0g [\u2212330\u00a0g, \u221272\u00a0g] lighter). Overall, there was no difference in the fetoplacental Doppler indices between groups but maternal glucose levels at OGTT were positively correlated with third\u2010trimester EFW and BW.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Fetuses of women with previous bariatric surgery are smaller during pregnancy and at birth, compared with those of women without such surgery, and this may be related to the lower maternal glucose levels seen in the former population. The fetoplacental circulation appears not to be altered by maternal weight loss surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Offspring of post\u2010bariatric women are smaller during pregnancy and at birth but this is not due to placental insufficiency.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.16105","type":"journal-article","created":{"date-parts":[[2020,1,19]],"date-time":"2020-01-19T10:30:25Z","timestamp":1579429825000},"page":"839-846","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Fetal growth and fetoplacental circulation in pregnancies following bariatric surgery: a prospective study"],"prefix":"10.1111","volume":"127","author":[{"given":"T","family":"Maric","sequence":"first","affiliation":[{"name":"Fetal Medicine Unit Chelsea and Westminster Hospital London UK"},{"name":"Academic Department of Obstetrics and Gynaecology Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Kanu","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Chelsea and Westminster Hospital London UK"},{"name":"Academic Department of Obstetrics and Gynaecology Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DC","family":"Muller","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics MRC\u2010PHE Centre for Environment and Health School of Public Health Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Tzoulaki","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics MRC\u2010PHE Centre for Environment and Health School of Public Health Imperial College London London UK"},{"name":"Department of Hygiene and Epidemiology University of Ioannina Medical School Ioannina Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MR","family":"Johnson","sequence":"additional","affiliation":[{"name":"Academic Department of Obstetrics and Gynaecology Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MD","family":"Savvidou","sequence":"additional","affiliation":[{"name":"Fetal Medicine Unit Chelsea and Westminster Hospital London UK"},{"name":"Academic Department of Obstetrics and Gynaecology Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60460-8"},{"key":"e_1_2_6_3_1","unstructured":"Health and Social Care Information Centre (HSCIC).Statistics on obesity physical activity and diet: England 2015. 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