{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T20:17:28Z","timestamp":1767212248405},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T00:00:00Z","timestamp":1623628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003122","name":"Ferring","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003122","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Postmenopausal nocturia is poorly understood. This study aimed to identify hormonal and lifestyle factors associated with nocturia and to understand the relative contribution of altered urine production and bladder storage dysfunction in women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, setting, population and methods<\/jats:title><jats:p>Women \u226540\u2009years presenting to public continence services were enrolled in a cross\u2010sectional study. A total of 153 participants completed a hormone status questionnaire, a validated nocturia causality screening tool and a 3\u2010day bladder diary. Descriptive statistics and logistic regression models for nocturia severity and bladder diary parameters were computed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 91.5% reported nocturia, 55% \u22652 \/night. There was a difference of 167.5\u2009ml (<jats:italic>P\u2009<\/jats:italic>&lt;\u20090.001) in nocturnal urine volume between women with nocturia \u22652 (median 736\u2009ml) versus less often (517\u2009ml). Significant predictors of self\u2010reported disruptive nocturia were age (odds ratio [OR] 1.04, 95% CI 1.002\u20131.073) and vitamin D supplementation (OR 2.33, 95% CI 1.11\u20134.91). Nocturnal polyuria was significantly more common with nocturia \u22652 compared with less frequent nocturia (<jats:italic>P\u2009<\/jats:italic>&lt;\u20090.002). Exercise for 150\u2009minutes a week was protective for nocturnal polyuria (OR 0.22, <jats:italic>P\u2009<\/jats:italic>=\u20090.001). Nocturia index &gt;1.3 was significantly predicted by age (OR 1.07, <jats:italic>P\u2009<\/jats:italic>&lt;\u20090.001), regular exercise (OR 0.41, <jats:italic>P\u2009<\/jats:italic>=\u20090.036), day flushes (OR 4.00, <jats:italic>P<\/jats:italic>\u2009=\u20090.013) and use of vitamin D (OR 2.34, <jats:italic>P<\/jats:italic>\u2009=\u20090.043). Maximum voided\u00a0volumes were significantly lower with nocturia \u22652 versus less often (night: 268\u2009ml versus 350\u2009ml; day: 200\u2009ml versus 290\u2009ml).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bothersome nocturia in postmenopausal women is associated with changes to both nocturnal diuresis and bladder storage. Regular physical activity, prolapse reduction and oestrogen replacement may be adjunctive in managing bothersome nocturia in women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.16752","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T11:29:29Z","timestamp":1621855769000},"page":"812-819","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The association between nocturia, hormonal symptoms and bladder parameters in women: an\u00a0observational study"],"prefix":"10.1111","volume":"129","author":[{"given":"WF","family":"Bower","sequence":"first","affiliation":[{"name":"Department of Medicine &amp; Aged Care The Royal Melbourne Hospital Parkville VIC Australia"},{"name":"Department of Sub\u2010Acute Care Services The Royal Melbourne Hospital Parkville VIC Australia"},{"name":"Faculty of Medicine, Dentistry &amp; Health Sciences The University of Melbourne Parkville VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GE","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Medicine &amp; Aged Care The Royal Melbourne Hospital Parkville VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DM","family":"Whishaw","sequence":"additional","affiliation":[{"name":"Department of Medicine &amp; Aged Care The Royal Melbourne Hospital Parkville VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CF","family":"Ervin","sequence":"additional","affiliation":[{"name":"Department of Sub\u2010Acute Care Services The Royal Melbourne Hospital Parkville VIC Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AC","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology Westmead Hospital University of Sydney Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KH","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Urogynaecology St George Hospital University of New South Wales Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23000"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09763.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.05.093"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.09.108"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000600"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(98)00093-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-020-00916-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13774"},{"key":"e_1_2_6_10_1","first-page":"68","article-title":"Reliability testing of the TANGO short\u2010form nocturia screening tool","volume":"23","author":"Rose GE","year":"2017","journal-title":"Aust N Z Continence J"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24029"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23272"},{"key":"e_1_2_6_13_1","first-page":"14","article-title":"Sample size calculation in medical studies","volume":"6","author":"Pourhoseingholi MA","year":"2013","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"e_1_2_6_14_1","volume-title":"penEpi: Open Source Epidemiologic Statistics for Public Health","author":"Dean AG"},{"key":"e_1_2_6_15_1","first-page":"388","article-title":"Diagnostic and therapeutic recommendations for patients with nocturia","volume":"70","author":"Miot\u0142a P","year":"2017","journal-title":"Central Eur J Urol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000727"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12727"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2015.1078206"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/3027036","article-title":"Vitamin D regulates the expressions of AQP\u20101 and AQP\u20104 in mice kidneys","volume":"2019","author":"Fu Y","year":"2019","journal-title":"BioMed Res Int"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-024-1057-0_9"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22219"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23939"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24331"},{"key":"e_1_2_6_24_1","unstructured":"https:\/\/www1.health.gov.au\/internet\/main\/publishing.nsf\/Content\/health\u2010pubhlth\u2010strateg\u2010phys\u2010act\u2010guidelines. Accessed 1 May 2020."},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22306"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-014-1396-0"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.23914"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.16752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1471-0528.16752","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.16752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T10:07:03Z","timestamp":1692958023000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.16752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,14]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1111\/1471-0528.16752"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.16752","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,14]]},"assertion":[{"value":"2021-04-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}