{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:05:04Z","timestamp":1790665504670,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the risk of spontaneous preterm birth (sPTB) associated with genital mycoplasma infection in asymptomatic women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Public and private health services in Ribeir\u00e3o Preto, SP, Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>A cohort of 1349 asymptomatic women with a singleton pregnancy at 20\u201325\u2009weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants completed a sociodemographic and clinical history questionnaire during the prenatal visit and provided cervicovaginal samples for the evaluation of <jats:italic>Mycoplasma hominis<\/jats:italic> (Mh), <jats:italic>Ureaplasma<\/jats:italic>\u2009spp. and bacterial vaginosis (BV). For gestational outcome, information about the delivery was assessed and sPTB was defined as a birth that occurred before 37\u2009weeks of gestation. The association between variables and the risk of sPTB was evaluated using logistic regression analysis to estimate the odds ratios (ORs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Genital mycoplasma infection and prematurity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of sPTB and genital mycoplasma was 6.8 and 18%, respectively. The infection was not a risk factor for sPTB (aOR 0.66, 95%\u2009CI 0.32\u20131.35), even when Mh and <jats:italic>Ureaplasma<\/jats:italic>\u2009spp. were found together (<jats:italic>P<\/jats:italic>\u2009=\u20090.83). Pregnant women with genital mycoplasma infections had greater BV (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), but this vaginal microbiota condition was not associated with sPTB (<jats:italic>P<\/jats:italic>\u2009=\u20090.35). Regarding the risk factors associated with sPTB, a previous history of sPTB (aOR 12.06, 95%\u2009CI 6.21\u201323.43) and a cervical length of \u22642.5\u2009cm (aOR 3.97, 95%\u2009CI 1.67\u20139.47) were significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Genital mycoplasma infection was not a risk factor for sPTB, even in the presence of other abnormal vaginal microbiota.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Genital mycoplasma infection was not a risk for sPTB, even when associated with bacterial vaginosis (BV).<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.16949","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T16:39:30Z","timestamp":1632501570000},"page":"273-281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Genital mycoplasma infection and spontaneous preterm birth outcome: a prospective cohort study"],"prefix":"10.1111","volume":"129","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6421-5575","authenticated-orcid":false,"given":"GKP","family":"Cunha","sequence":"first","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LB","family":"Bastos","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SF","family":"Freitas","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RC","family":"Cavalli","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SM","family":"Quintana","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeir\u00e3o Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30451-0"},{"key":"e_1_2_7_3_1","unstructured":"Brasil. 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