{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:47:48Z","timestamp":1779187668361,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,1,29]],"date-time":"2022-01-29T00:00:00Z","timestamp":1643414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the risk of spontaneous preterm birth (sPTB) associated with the length of second stage of labour in the first term delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Women with first two consecutive singleton births and the first birth at term. Those who did not reach the second stage of labour in the first delivery were excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Charts from 2007 to 2019 were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Rate of sPTB (&lt;37\u00a0weeks of gestation) in the second delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 13\u00a0958 women who met study inclusion criteria, 1464 (10.5%) parturients had a prolonged second stage (\u2265180\u00a0min) in their first term delivery. The rate of sPTB in the second delivery was similar in those with and without a prolonged second stage in first delivery (2.8% versus 2.8%; adjusted odds ratio [aOR] 1.35, 95% CI 0.96\u20131.90). After adjustment for mode of delivery, prolonged second stage was also not associated with subsequent sPTB in those who delivered by spontaneous and operative vaginal delivery. Those delivered by second\u2010stage caesarean section in the first delivery had a higher risk of sPTB in the second delivery (25\/526, 4.8%; aOR 2.66, 95% CI 1.71\u20134.12; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), with a more pronounced risk in those with second\u2010stage caesarean following a prolonged second stage of labour (15\/259, 5.8%; aOR 3.40, 95% CI 1.94\u20135.94; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Second\u2010stage duration in a first term vaginal delivery is not associated with subsequent sPTB. The risk of sPTB is increased following second\u2010stage caesarean section, particularly if performed after a prolonged second stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Tweetable abstract<\/jats:title><jats:p>Second\u2010stage caesarean delivery, particularly after prolonged second stage, increases the risk of preterm birth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.17102","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T15:09:55Z","timestamp":1642086595000},"page":"1743-1749","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Duration of the second stage of labour and risk of subsequent spontaneous preterm birth"],"prefix":"10.1111","volume":"129","author":[{"given":"Geffen","family":"Kleinstern","sequence":"first","affiliation":[{"name":"School of Public Health University of Haifa  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy","family":"Zigron","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shay","family":"Porat","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua I.","family":"Rosenbloom","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4875-1455","authenticated-orcid":false,"given":"Misgav","family":"Rottenstreich","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yishay","family":"Sompolinsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2472-5204","authenticated-orcid":false,"given":"Amihai","family":"Rottenstreich","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Hadassah\u2010Hebrew University Medical Centre and Faculty of Medicine, Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3769"},{"key":"e_1_2_11_3_1","volume-title":"March of Dimes, PMNCH, Save the Children,WHO. 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