{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T23:44:07Z","timestamp":1793231047791,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T00:00:00Z","timestamp":1682985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2023,11]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To determine whether laparoscopic sacrocolpopexy (LSC) or vaginal sacrospinous fixation (VSF) is the most optimal surgical treatment in patients with POP\u2010Q\u2009stage \u22652 vaginal vault prolapse (VVP).<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Multicentre randomised controlled trial (RCT) and prospective cohort study alongside.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Seven non\u2010university teaching hospitals and two university hospitals in the Netherlands.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n Patients with symptomatic post\u2010hysterectomy vaginal vault prolapse, requiring surgical treatment.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Randomisation in a 1:1 ratio to LSC or VSF. Evaluation of prolapse was done using the pelvic organ prolapse quantification (POP\u2010Q). All participants were asked to fill in various Dutch validated questionnaires 12\u2009months postoperatively.<\/jats:p>\n <\/jats:sec>\n \n Main outcome measures<\/jats:title>\n Primary outcome was disease\u2010specific quality of life. Secondary outcomes included composite outcome of success and anatomical failure. Furthermore, we examined peri\u2010operative data, complications and sexual function.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 179 women, 64 women randomised and 115 women, participated in a prospective cohort. Disease\u2010specific quality of life did not differ after 12\u2009months between the LSC and VSF group in the RCT and the cohort (RCT:\n P<\/jats:italic>\n \u2009=\u20090.887; cohort:\n P<\/jats:italic>\n \u2009=\u20090.704). The composite outcomes of success for the apical compartment, in the RCT and cohort, were 89.3% and 90.3% in the LSC group and 86.2% and 87.8% in the VSF group, respectively (RCT:\n P<\/jats:italic>\n \u2009=\u20090.810; cohort:\n P<\/jats:italic>\n \u2009=\u20090.905). There were no differences in number of reinterventions and complications between both groups (reinterventions RCT:\n P<\/jats:italic>\n \u2009=\u20090.934; cohort:\n P<\/jats:italic>\n \u2009=\u20090.120; complications RCT:\n P<\/jats:italic>\n \u2009=\u20090.395; cohort:\n P<\/jats:italic>\n \u2009=\u20090.129).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n LSC and VSF are both effective treatments for vaginal vault prolapse, after a follow\u2010up period of 12\u2009months.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1471-0528.17525","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T02:19:39Z","timestamp":1683080379000},"page":"1542-1551","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Laparoscopic sacrocolpopexy versus vaginal sacrospinous fixation for vaginal vault prolapse: a randomised controlled trial and prospective cohort (\n SALTO<\/scp>\n \u20102 trial)"],"prefix":"10.1111","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7984-9223","authenticated-orcid":false,"given":"Anique M. J.","family":"van Oudheusden","sequence":"first","affiliation":[{"name":"Department of Gynaecology and Obstetrics VieCuri Medical Centre Venlo The Netherlands"},{"name":"Department of Gynaecology and Obstetrics GROW, School for Oncology & Reproduction, Maastricht University Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e8lanie N.","family":"van IJsselmuiden","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics GROW, School for Oncology & Reproduction, Maastricht University Maastricht The Netherlands"},{"name":"Department of Gynaecology and Obstetrics Isala Medical Centre Zwolle The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah F.","family":"Menge","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Reinier de Graaf Guesthouse Delft The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Lotte W. M.","family":"Coolen","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Zuyderland Medical Centre Sittard\u2010Geleen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joggem","family":"Veen","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics M\u00e1xima Medical Centre Veldhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo W. F.","family":"van Eijndhoven","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Isala Medical Centre Zwolle The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane","family":"Dietz","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Catharina Hospital Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten B.","family":"Kluivers","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Radboud University Medical Centre Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilbert A.","family":"Spaans","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Maastricht University Medical Centre + Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Vollebregt","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Spaarne Gasthuis Haarlem The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geerte","family":"van de Pol","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Gelre Hospitals Apeldoorn The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine M.","family":"Radder","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics OLVG Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Marinus","family":"van der Ploeg","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Martini Hospital Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander M. J.","family":"van Kuijk","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA) Maastricht University Medical Centre + Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlies Y.","family":"Bongers","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics GROW, School for Oncology & Reproduction, Maastricht University Maastricht The Netherlands"},{"name":"Department of Gynaecology and Obstetrics M\u00e1xima Medical Centre Veldhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.01.012"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2757-y"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-008-0718-4"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-020-04591-z"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0902-1"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/528636"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3296-5"},{"key":"e_1_2_12_9_1","first-page":"1","article-title":"Laparoscopic sacrocolpopexy versus abdominal sacrocolpopexy for vaginal vault prolapse: long\u2010term follow\u2010up of a randomized controlled trial","volume":"16","author":"Oudheusden AMJ","year":"2022","journal-title":"Int Urogynecol J"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-018-3832-y"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta24130"},{"issue":"10","key":"e_1_2_12_12_1","article-title":"Surgery for women with apical vaginal prolapse","volume":"1","author":"Maher C","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-021-04823-w"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-017-0402-2"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-14-112"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16242"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181b2b1ae"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2169-9"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70243-0"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.10038"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00734.x"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-1069-5"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-003-1063-2"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2692-y"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00001.x"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h3717"}],"container-title":["BJOG: An International Journal of Obstetrics & Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.17525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T02:56:37Z","timestamp":1716951397000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.17525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,2]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/1471-0528.17525"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.17525","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,2]]},"assertion":[{"value":"2022-11-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}