{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T22:36:35Z","timestamp":1788561395278,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/V006835\/1"],"award-info":[{"award-number":["MR\/V006835\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To quantify maternal hypertensive disorder of pregnancy (HDP) prevalence in late preterm and term infants admitted to neonatal units (NNU) and assess opportunities to avoid admissions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A retrospective population\u2010based study using the National Neonatal Research Database.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>England and Wales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>Infants born \u226534\u2009weeks\u2019 gestation admitted to NNU between 2012 and 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Outcomes in HDP infants are compared with non\u2010HDP infants using regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Hypertensive disorder of pregnancy, primary reason for admission, clinical diagnoses and resource use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      16\u2009059\/136\u2009220 (11.8%) of late preterm (34\n                      <jats:sup>+0<\/jats:sup>\n                      to 36\n                      <jats:sup>+6<\/jats:sup>\n                      weeks\u2019 gestation) and 14\u2009885\/284\u2009646 (5.2%) of term (\u226537\u2009weeks\u2019 gestation) admitted infants were exposed to maternal HDP. The most common primary reasons for HDP infant admission were respiratory disease (28.3%), prematurity (22.7%) and hypoglycaemia (16.4%). HDP infants were more likely to be admitted with primary hypoglycaemia than were non\u2010HDP infants (odds ratio [OR] 2.1, 95% confidence interval [CI] 2.0\u20132.2,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.0001). 64.5% of HDP infants received i.v. dextrose. 35.7% received mechanical or non\u2010invasive ventilation. 8260\/30\u2009944 (26.7%) of HDP infants received intervention for hypoglycaemia alone (i.v. dextrose) with no other major intervention (respiratory support, parenteral nutrition, central line, arterial line or blood transfusion).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The burden of maternal HDP on late preterm and term admissions to NNU is high, with hypoglycaemia and respiratory disease being the main drivers for admission. Over one in four were admitted solely for management of hypoglycaemia. Further research should determine whether maternal antihypertensive agent choice or postnatal pathways may reduce NNU admission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.17574","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:04:05Z","timestamp":1687219445000},"page":"88-98","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["The contribution of hypertensive disorders of pregnancy to late preterm and term admissions to neonatal units in the UK 2012\u20132020 and opportunities to avoid admission: A population\u2010based study using the National Neonatal Research Database"],"prefix":"10.1111","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7081-6839","authenticated-orcid":false,"given":"Frances","family":"Conti\u2010Ramsden","sequence":"first","affiliation":[{"name":"Department of Women and Children's Health King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Fleminger","sequence":"additional","affiliation":[{"name":"Department of Women and Children's Health King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Lanoue","sequence":"additional","affiliation":[{"name":"Neonatal Medicine, School of Public Health, Faculty of Medicine Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy C.","family":"Chappell","sequence":"additional","affiliation":[{"name":"Department of Women and Children's Health King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2898-553X","authenticated-orcid":false,"given":"Cheryl","family":"Battersby","sequence":"additional","affiliation":[{"name":"Neonatal Medicine, School of Public Health, Faculty of Medicine Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the UK Neonatal Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651\u20102227.2012.02787.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJOPEN\u20102017\u2010016050"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.120080"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(10)60279\u20106"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g2301"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2016.04.020"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20132"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2109523"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1015"},{"key":"e_1_2_11_11_1","volume-title":"Chesley's hypertensive disorders in pregnancy","author":"Taylor RN","year":"2015"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.005526"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016\u20100731"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002252.pub4"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000001456"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0248774"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.AJOGMF.2022.100687"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41372\u2010020\u20100589\u20101"},{"key":"e_1_2_11_19_1","unstructured":"NICE.Overview | Preterm labour and birth | Guidance. 2015 [cited 2023 Feb 1]. 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