{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:20:53Z","timestamp":1773274853589,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T00:00:00Z","timestamp":1719878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the positive rate of late\u2010onset gestational diabetes mellitus (GDM) by additional fasting blood glucose (FBG) screening at 32\u201334 gestational weeks (GW) and analyse the perinatal outcomes of late\u2010onset GDM after standard treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>An Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single centre in China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>1130 singleton pregnancies with negative GDM screening in their first and second trimester.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Additional FBG testing was performed at 32\u201334 GW. Pregnancies with FBG \u22655.1\u2009mmol\/L were diagnosed as GDM and received standardized treatment. Perinatal outcomes were collected and compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Diagnosis of late\u2010onset GDM, obstetric and neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>6.3% (71\/1130) of participants had FBG values \u22655.1\u2009mmol\/L and were diagnosed with late\u2010onset GDM. Sixty\u2010five (91.5%) were treated by dietary therapy and 6 (8.5%) by insulin therapy. The perinatal outcomes of full\u2010term delivery were compared. The incidence of macrosomia (22.7% vs. 5.1%, adjusted odds ratio (aOR) 5.51, 95% confidence interval (CI) 1.83\u201316.61, <jats:italic>p<\/jats:italic>\u2009=\u20090.002) and NICU transferring (18.3% vs. 10.1%, aOR 1.94, 95% CI 1.01\u20133.74, <jats:italic>p<\/jats:italic>\u2009=\u20090.046) was significantly higher in late\u2010onset GDM group than that in FBG &lt;5.1\u2009mmol\/L group. Elevated FBG was associated with overweight or obesity during pregnancy (54.9% vs. 34.9%, OR 2.27, 95% CI 1.40\u20133.68, <jats:italic>p<\/jats:italic>\u2009=\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>6.3% of singleton pregnancies with normal GDM screening results in the first and second trimester were found to have late\u2010onset GDM by additional FBG screening at 32\u201334 GW, and their risk of macrosomia during a full\u2010term pregnancy remains significantly higher after standard treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.17897","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T07:38:40Z","timestamp":1719905920000},"page":"1715-1724","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Fasting blood glucose as a screening measure for late\u2010onset gestational diabetes in the third trimester"],"prefix":"10.1111","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1491-544X","authenticated-orcid":false,"given":"Xiaoxia","family":"Tang","sequence":"first","affiliation":[{"name":"Shanghai General Hospital of Nanjing Medical University  Shanghai China"},{"name":"The Affiliated Taizhou People's Hospital of Nanjing Medical University  Taizhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Wei","sequence":"additional","affiliation":[{"name":"The Affiliated Taizhou People's Hospital of Nanjing Medical University  Taizhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaohua","family":"Wu","sequence":"additional","affiliation":[{"name":"The Affiliated Taizhou People's Hospital of Nanjing Medical University  Taizhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sufang","family":"Wu","sequence":"additional","affiliation":[{"name":"Shanghai General Hospital of Nanjing Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707943"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000412"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(01)00496-9"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19113342"},{"issue":"11","key":"e_1_2_12_6_1","first-page":"CC01","article-title":"Normal pregnancy \u2010 a state of insulin resistance","volume":"8","author":"Sonagra AD","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc21\u2010S014"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020\u20107292(15)30033\u20103"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2017.10.038"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112141\u201020210917\u201000528"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12923"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.20007"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1190825"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X211055634"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884\u2010021\u201003730\u20108"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100042\u20101759865"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404\u2010023\u201007298\u2010w"},{"key":"e_1_2_12_18_1","volume-title":"Guideline No. MN21.33\u2010V6\u2010R26","author":"Queensland Clinical Guidelines. 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