{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:41:18Z","timestamp":1787013678106,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,1]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To correlate the clinical history with imaging findings of women with Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser (MRKH) syndrome.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Retrospective cohort study.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n A UK IOTA and ESGO\u2010certified tertiary referral centre for disorders of reproductive development.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n All patients with a diagnosis of MRKH and who had undergone an MRI pelvis between 1 January 2011 and 31 April 2021 were included.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n MRI images were analysed by specialist gynaecological radiologists. Clinical data was extracted from an electronic patient record system. Statistical analysis was computed in R (version 4.1.2), R base stats package and ggstatsplot (v0.5.0).<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n Clinical history and predefined imaging features.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n One hundred and thirty\u2010four patients were included. Median age at MRI was 18\u2009years (10\u201364\u2009years). Half (48.2%) of women presenting had a history of pain, most often abdominal (84.6%) or vaginal (9.2%). Remnants were identified in 91.8% of women (\n n<\/jats:italic>\n \u2009=\u2009123). 4.5% of women had imaging features of endometriosis (\n n<\/jats:italic>\n \u2009=\u20096). Women with a functional remnants were significantly more likely to experience pain (\n p<\/jats:italic>\n \u2009<\u20090.001). Pain history was not strongly associated with ectopic ovarian position. Common gynaecological pathology such as endometriosis, ovarian cysts and fibroids were also identified.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n We identify that majority of women with MRKH will have uterine remnants with a connecting fibrous band, and an ectopic ovarian position 44.0% of cases. Abdominal pain was significantly associated with functional remnants on MRI. Further work is required to identify how other gynaecological pathology impacts women with MRKH.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1471-0528.17928","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T04:54:54Z","timestamp":1723438494000},"page":"64-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Magnetic resonance imaging and clinical features of Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser syndrome: A 10\u2010year review from a dedicated specialist centre"],"prefix":"10.1111","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5828-8014","authenticated-orcid":false,"given":"Nina","family":"Cooper","sequence":"first","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Department of Metabolism, Digestion and Reproduction, Faculty of Medicine Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Al\u2010Memar","sequence":"additional","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Department of Metabolism, Digestion and Reproduction, Faculty of Medicine Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristofer","family":"Linton\u2010Reid","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Faculty of Medicine Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Edmonds","sequence":"additional","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuala","family":"Dixon","sequence":"additional","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cillian","family":"McNamara","sequence":"additional","affiliation":[{"name":"Department of Imaging Imperial College Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Fotopoulou","sequence":"additional","affiliation":[{"name":"Department of Disorders for Reproductive Development, Queen Charlotte's & Chelsea Hospital Imperial College Healthcare NHS Trust London UK"},{"name":"Department of Surgery and Cancer, Faculty of Medicine Imperial College London London United\u00a0Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine Van","family":"Ree","sequence":"additional","affiliation":[{"name":"Department of Imaging Imperial College Healthcare NHS Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishat","family":"Bharwani","sequence":"additional","affiliation":[{"name":"Department of Metabolism, Digestion and Reproduction, Faculty of Medicine Imperial College London London UK"},{"name":"Department of Imaging Imperial College Healthcare NHS Trust London 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