{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:03:45Z","timestamp":1767855825825,"version":"3.49.0"},"reference-count":69,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>We tested for the potential associations between maternal antenatal cannabis use disorders (CUD) and neonatal health outcomes using large linked administrative data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Population\u2010based retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The study was conducted in New South Wales, Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population or Sample<\/jats:title><jats:p>A total of 215\u2009879 singleton live births.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Generalised linear models (GLMs) fitted using log\u2010binomial regression to estimate risk ratios (RRs) with the corresponding 95% confidence intervals (95% CI). Additionally, we conducted a propensity score matching (PSM) analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>The outcomes include preterm births (PTB), low birth weight (LBW), small for gestational age (SGA), 5\u2010min lower Apgar scores and admission to the neonatal intensive care unit (NICU).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In unmatched analyses, antenatal CUD was associated with increased risks for all adverse neonatal outcomes (adjusted risk ratio [RR] ranging from 1.47 [95% CI: 1.01, 2.14] for 5\u2010min lower APGAR scores to 2.58 [95% CI 2.28, 2.91] for PTB). In PSM analyses, we observed slightly attenuated risks of PTB (RR\u2009=\u20091.98 [1.70, 2.31]), LBW (RR\u2009=\u20092.46 [2.13, 2.84]), SGA (RR\u2009=\u20091.84 [1.44, 2.35]) and admission to NICU (RR\u2009=\u20091.91 [1.49, 2.45]) after matching by covariates. However, we found no significant association between antenatal CUD and 5\u2010min low APGAR scores (RR\u2009=\u20091.47 [0.94, 2.30]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that maternal antenatal exposure to CUD is associated with a range of adverse neonatal outcomes. This study highlights that targeted interventions focusing on antenatal counselling are recommended to mitigate risks associated with maternal cannabis use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.18024","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T04:19:57Z","timestamp":1732594797000},"page":"529-538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Maternal Cannabis Use Disorder and Neonatal Health Outcomes: A Data Linkage Study"],"prefix":"10.1111","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0499-4690","authenticated-orcid":false,"given":"Abay Woday","family":"Tadesse","sequence":"first","affiliation":[{"name":"School of Population Health Curtin University  Bentley Australia"},{"name":"Dream Science and Technology College  Dessie Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Betts","sequence":"additional","affiliation":[{"name":"School of Population Health Curtin University  Bentley Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4041-6129","authenticated-orcid":false,"given":"Berihun Assefa","family":"Dachew","sequence":"additional","affiliation":[{"name":"School of Population Health Curtin University  Bentley Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Getinet","family":"Ayano","sequence":"additional","affiliation":[{"name":"School of Population Health Curtin University  Bentley Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Alati","sequence":"additional","affiliation":[{"name":"School of Population Health Curtin University  Bentley Australia"},{"name":"Institute for Social Sciences Research The University of Queensland  Indooroopilly Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"issue":"21","key":"e_1_2_10_2_1","first-page":"591","article-title":"Diagnostic and Statistical Manual of Mental Disorders","volume":"21","author":"APA","year":"2013","journal-title":"American Psychiatric Association"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11469-022-00999-4"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2020.106479"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14234"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.0138"},{"key":"e_1_2_10_7_1","first-page":"33","volume-title":"Addiction Medicine: A Case and Evidence\u2010Based Guide","author":"Cannabis P. 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