{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:17:56Z","timestamp":1790083076871,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the effects of chorioamnionitis on uterine activity and to investigate associations between external and intrauterine monitoring methods and neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Secondary analysis of a randomised controlled trial cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Two labour wards, in a university tertiary hospital and a central hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Parturients with singleton pregnancies, gestational age \u2265\u200937\u2009weeks and fetus in cephalic position. Clinical chorioamnionitis developed in 8.6% of cases (<jats:italic>n<\/jats:italic>\u2009=\u2009130\/1504).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Analyses of uterine activity (contractions\/10\u2009min or intrauterine pressure in Montevideo units) during the 4\u2009h before birth adjusted for maternal characteristics and intrapartum factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Uterine activity with or without chorioamnionitis and the intervention of external versus intrauterine monitoring in relation to fetal distress (admission to neonatal intensive care with umbilical artery pH \u2264\u20097.10 or 5\u2010min Apgar score &lt;\u20097), stratified by chorioamnionitis status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Uterine contraction frequency\/10\u2009min decreased in labours with chorioamnionitis during the final hour preceding birth (4.2 [SD 1.1] vs. 3.9 [SD 1.2], adjusted regression coefficient \u22120.383, 95% CI \u22120.654 to \u22120.112, <jats:italic>p<\/jats:italic>\u2009=\u20090.006) compared to non\u2010infected labors. In chorioamnionitis cases, mean frequency\/10\u2009min during last 4\u2009h was higher with external versus intrauterine monitoring (4.2 [SD 0.8] vs. 3.8 [SD 0.9], MD 0.39, 95% CI 0.02\u20130.76, <jats:italic>p<\/jats:italic>\u2009=\u20090.038), and the intrauterine monitoring group had a lower incidence of fetal distress (6.7% vs. 23.1%, OR 0.24, 95% CI 0.07\u20130.79, <jats:italic>p<\/jats:italic>\u2009=\u20090.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Chorioamnionitis impairs uterine activity. Intrauterine monitoring may provide more accurate contraction analysis than external tocodynamometry and help reduce fetal compromise during labours complicated by chorioamnionitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.18076","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T03:14:58Z","timestamp":1736997298000},"page":"795-804","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Intrauterine Contraction Monitoring in Chorioamnionitis: A Secondary, Blinded Analysis of a Randomised Controlled Trial Cohort"],"prefix":"10.1111","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6324-9928","authenticated-orcid":false,"given":"Milla","family":"Juhantalo","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynaecology Tampere University Hospital, Wellbeing Services County of Pirkanmaa  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuija","family":"Hautakangas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynaecology Wellbeing Services County of Central Finland\/Hospital Nova of Central Finland  Jyv\u00e4skyl\u00e4 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Outi","family":"Palom\u00e4ki","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynaecology Tampere University Hospital, Wellbeing Services County of Pirkanmaa  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukka","family":"Uotila","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynaecology Tampere University Hospital, Wellbeing Services County of Pirkanmaa  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002236"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2010.02.003"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.09.044"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002984"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1700861"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90356-6"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.04.001"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0902748"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16343"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2011.582905"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.03.003"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719118778819"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32231-1"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-019-0322-0"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.03.023"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2022.05.011"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.06.011"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14838"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001246"},{"key":"e_1_2_12_21_1","unstructured":"COMET Initiative \u201cDevelopment of a Core Outcome Set for Maternal and Perinatal Health Research and Surveillance in Light of Emerging and Ongoing Epidemic Threats \u201d2024 November 22 https:\/\/www.cometinitiative.org\/Studies\/Details\/3085."},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.11.038"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.06.018"},{"issue":"6","key":"e_1_2_12_24_1","first-page":"909","article-title":"Chorioamnionitis and Uterine Function","volume":"95","author":"Mark S.","year":"2000","journal-title":"Obstetrics & Gynecology"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17005"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14948"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000005447"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; 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