{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T09:53:21Z","timestamp":1792403601799,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T00:00:00Z","timestamp":1748390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T00:00:00Z","timestamp":1748390400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the association between caesarean birth in the second stage of labour and the risk of spontaneous preterm birth in a subsequent pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Nationwide register\u2010based cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The Danish Medical Birth Registry and The Danish National Patient Register from 1997 to 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>Women with at least two consecutive births (index birth and subsequent birth) where the index birth was a term singleton.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Women with spontaneous preterm subsequent birth were compared according to the mode of index birth, including vaginal, prelabour caesarean, first stage caesarean and second\u2010stage caesarean.<\/jats:p>\n                    <jats:p>Statistical analysis was performed using multiple logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure<\/jats:title>\n                    <jats:p>Spontaneous birth before 37\u2009+\u20090 gestational weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 376\u2009414 women met the inclusion criteria. Distribution of mode of index birth was vaginal 318\u2009117 (84.5%), prelabour caesarean 15\u2009373 (4.1%), first stage caesarean 37\u2009547 (10.0%) and second\u2010stage caesarean 5377 (1.4%), respectively. The rate of subsequent preterm birth was 1.7%. Compared to vaginal birth, a second\u2010stage caesarean was associated with an increased risk of preterm birth in a subsequent pregnancy (adjusted odds ratio [aOR] 1.46, 95% confidence interval [CI] 1.21\u20131.77). Similarly, compared to first stage caesarean, a second\u2010stage caesarean was associated with an increased risk of preterm birth in the subsequent pregnancy, with an aOR of 1.41 (95% CI 1.15\u20131.74).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Second\u2010stage caesarean in a previous term pregnancy is associated with an increased risk of spontaneous preterm birth in a subsequent pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.18225","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T03:00:04Z","timestamp":1748487604000},"page":"1585-1593","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Risk of Spontaneous Preterm Birth in a Subsequent Pregnancy After Full Dilatation Caesarean Birth: A Nationwide Cohort Study"],"prefix":"10.1111","volume":"132","author":[{"given":"Sara","family":"Acker","sequence":"first","affiliation":[{"name":"Department of Gynaecology and Obstetrics Copenhagen University Hospital \u2013 Amager and Hvidovre  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina Hein","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Copenhagen University Hospital \u2013 Amager and Hvidovre  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea Kirstine","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9856-6621","authenticated-orcid":false,"given":"Julie","family":"Glavind","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6297-2783","authenticated-orcid":false,"given":"Maria","family":"Jeppegaard","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Copenhagen University Hospital \u2013 Amager and Hvidovre  Hvidovre Denmark"},{"name":"Department of Gynaecology and Obstetrics Copenhagen University Hospital \u2013 Holbaek  Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics Copenhagen University Hospital \u2013 Amager and Hvidovre  Hvidovre Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(21)00311-4"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13195"},{"key":"e_1_2_12_4_1","unstructured":"WHO \u201cBorn Too Soon: Decade of Action on Preterm Birth \u201d2023."},{"key":"e_1_2_12_5_1","unstructured":"D. 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