{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T17:25:06Z","timestamp":1769793906620,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To study the association between previous use of levonorgestrel intrauterine system (LNG\u2010IUS) and endometrial thickness (EMT) in women undergoing in\u00a0vitro fertilisation (IVF)\/intracytoplasmic sperm injection (ICSI) cycles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Multicentre historical cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Eight Danish public and private fertility clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>12786 women aged 18\u201346\u2009years contributing with an EMT measurement from 22\u2009464 different IVF\/ICSI treatment cycles between 2000 and 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Exposure was previous use of LNG\u2010IUS, combined oral contraceptive pills (OCPs), progeste\u2010only pills (POPs), no\/other contraception or combined, cumulated use of contraception when more contraceptives had been used during the inclusion period. Further, ever use of LNG\u2010IUS was categorised into 0\u20133\u2009years, &gt; 3\u20136\u2009years, &gt; 6\u20139\u2009years and &gt;\u20099\u2009years. Mixed effect logistic regression adjusted for age, BMI, smoking, educational level, total FSH dose and fertility clinic was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measure (s)<\/jats:title>\n                    <jats:p>EMT (&lt;\u20097\u2009mm \u2265\u20097\u2009mm).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Statistically significantly higher odds of EMT \u2265\u20097\u2009mm were found for OCPs [odds ratio (OR) 3.53 (95% confidence interval (95% CI) 1.29\u20139.65)], POPs [OR 6.43, (95% CI 1.45\u201328.63)] and no\/other contraception [OR 6.67, (95% CI 2.37\u201318.74]) relative to LNG\u2010IUS in IVF\/ICSI cycles. Further, all duration categories of ever use of LNG\u2010IUS were associated with statistically significantly lower odds of obtaining an EMT \u2265\u20097\u2009mm compared to no\/other contraception.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study, previous use of LNG\u2010IUS was associated with decreased endometrial growth in women undergoing IVF\/ICSI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.18295","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T03:35:30Z","timestamp":1752723330000},"page":"1681-1688","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hormonal Contraception and Endometrial Thickness in\n                    <scp>IVF<\/scp>\n                    \/\n                    <scp>ICSI<\/scp>\n                    Cycles: A Multicentre Historical Cohort Study"],"prefix":"10.1111","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2799-2855","authenticated-orcid":false,"given":"Mette Peters","family":"Michaelsen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Health Science and Technology Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura C\u00e6cilie","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Health Science and Technology Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aalborg University Hospital  Aalborg 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