{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T23:14:44Z","timestamp":1772493284471,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare childbirth satisfaction and obstetrical outcomes with outpatient versus inpatient induction of labour (IOL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Multicentre, randomised\u2010controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Eight hospitals in Norway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>Women scheduled for IOL, single cephalic presentation, \u2265\u200937\u2009weeks, no previous uterine scar, and low risk of complications by predefined criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Included women received oral misoprostol (25\u2009\u03bcg) for up to 48\u2009h as the primary induction agent. The Childbirth Experience Questionnaire (CEQ) and the Experience with Induction Tool (EXIT) were used to assess childbirth satisfaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>CEQ\u2010score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Secondary Outcome Measures<\/jats:title>\n                    <jats:p>EXIT questionnaire and obstetrical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 283 women randomised, 152 women were allocated to outpatient and 131 to inpatient settings. Outpatient IOL resulted in a more positive childbirth experience (mean CEQ\u2010score 3.1 [0.44] vs. 3.0 [0.45]), mean difference 0.14, 95% CI (0.02\u20130.25),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02. In the outpatient group, women were admitted to the hospital 21\u2009h shorter before delivery (15 vs. 36\u2009h, mean difference \u221221, 95% CI \u221225 to \u221217,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Obstetrical outcomes were similar, and there were no cases of hyperstimulation before labour or serious adverse events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Outpatient IOL using oral misoprostol was associated with high maternal satisfaction, with 89% of women expressing a preference for this method in future pregnancies. Labour outcomes appear comparable to those of inpatient induction, while outpatient management also provides potential cost benefits due to shorter hospital admission. We advocate for this method as a feasible option for appropriately selected women; however, the occurrence of rare adverse events necessitates further investigation through larger studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      ID NCT05144048.\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT05144048?locStr=Norway&amp;country=Norway&amp;cond=Induction%20of%20Labor&amp;rank=1\">https:\/\/clinicaltrials.gov\/study\/NCT05144048?locStr=Norway&amp;country=Norway&amp;cond=Induction%20of%20Labor&amp;rank=1<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.18296","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T09:47:21Z","timestamp":1753350441000},"page":"1562-1573","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outpatient Versus Inpatient Induction of Labour With Oral Misoprostol: A Multicentre Randomised\u2010Controlled Trial"],"prefix":"10.1111","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4732-7989","authenticated-orcid":false,"given":"Fride E.","family":"Austad","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology S\u00f8rlandet Hospital Trust  Kristiansand Norway"},{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2931-2668","authenticated-orcid":false,"given":"J\u00f6rg","family":"Kessler","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynaecology Haukeland University Hospital  Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth Balstad","family":"Magnussen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology St. Olavs University Hospital  Trondheim Norway"},{"name":"Norwegian University of Science and Technology  Trondheim Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Are Hugo","family":"Pripp","sequence":"additional","affiliation":[{"name":"Oslo Centre of Biostatistics and Epidemiology, Research Support Services Oslo University Hospital  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janne","family":"Rossen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology S\u00f8rlandet Hospital Trust  Kristiansand Norway"},{"name":"Institute of Clinical Medicine University of Oslo  Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14447"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0297857"},{"key":"e_1_2_11_4_1","unstructured":"The Medical Birth Registry of Norway [Statistics Bank] 2024 https:\/\/statistikkbank.fhi.no\/mfr\/."},{"issue":"5","key":"e_1_2_11_5_1","article-title":"Induction of Labour for Improving Birth Outcomes for Women at or Beyond Term","volume":"5","author":"Middleton P.","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l6131"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14389"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60736-4"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.07.014"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.3635"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.01.002"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01845-1"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23563"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17794"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14626"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17986"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.15092"},{"issue":"6","key":"e_1_2_11_18_1","article-title":"Low\u2010Dose Oral Misoprostol for Induction of Labour","volume":"6","author":"Kerr R. 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