{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:29:33Z","timestamp":1792531773587,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore associations between pregnancy metabolic complications and maternal cardiometabolic health 10\u2009years postpartum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective Longitudinal Cohort Study following a randomised controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single\u2010centre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>Pregnancy metabolic complication (pregnancy\u2010induced hypertension, impaired glucose tolerance, or gestational diabetes) versus an uncomplicated pregnancy in secundigravid women who previously delivered a macrosomic infant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Health and lifestyle data were obtained from 422 women during pregnancy and again 10\u2009years postpartum. Anthropometry, dual\u2010energy X\u2010ray absorptiometry scans, and non\u2010fasting blood samples were recorded 10\u2009years postpartum. Unadjusted and adjusted linear regression explored associations between pregnancy metabolic complications and cardiometabolic markers with adjustment for potential confounders (study group allocation, age at follow\u2010up, maternal ethnicity, early pregnancy body mass index (BMI), use of cardiometabolic medications, maternal smoking at 10\u2009years postpartum, and socio\u2010economic status).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Cardiometabolic risk profile 10\u2009years postpartum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 422 women, 27.7% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009117) experienced a metabolic complication in pregnancy. Pregnancy metabolic complications were associated with greater postpartum weight retention (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20091.72, 95% CI 0.08, 3.36), higher BMI (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.70, 95% CI 0.09, 1.31), greater visceral adipose tissue mass (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.12, 95% CI 0.01, 0.23), greater total cholesterol (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.36, 95% CI 0.15, 0.58), greater LDL\u2010cholesterol (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.29, 95% CI 0.09, 0.50), greater triglycerides (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.06, 95% CI 0.03, 0.32), and greater glucose (\n                      <jats:italic>\u00df<\/jats:italic>\n                      \u2009=\u20090.22, 95% CI 0.03, 0.40) at 10\u2009years postpartum.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pregnancy metabolic complications were associated with an altered cardiometabolic risk profile 10\u2009years postpartum.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.70092","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:27:44Z","timestamp":1764048464000},"page":"739-750","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Metabolic Complications in Pregnancy on Later Life Maternal Cardiometabolic Health: Findings From the\n                    <scp>ROLO<\/scp>\n                    Longitudinal Cohort Study"],"prefix":"10.1111","volume":"133","author":[{"given":"Kristyn","family":"Dunlop","sequence":"first","affiliation":[{"name":"UCD Perinatal Research Centre, School of Medicine University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Callanan","sequence":"additional","affiliation":[{"name":"UCD Perinatal Research Centre, School of Medicine University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaat","family":"Philippe","sequence":"additional","affiliation":[{"name":"School of Public Health, Physiotherapy and Sports Science University College Dublin  Belfield Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"McNestry","sequence":"additional","affiliation":[{"name":"UCD Perinatal Research Centre, School of Medicine University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Douglass","sequence":"additional","affiliation":[{"name":"School of Public Health, Physiotherapy and Sports Science University College Dublin  Belfield Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Segurado","sequence":"additional","affiliation":[{"name":"Centre for Support and Training in Analysis and Research University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel K.","family":"Crowley","sequence":"additional","affiliation":[{"name":"School of Medicine University College Dublin  Dublin Ireland"},{"name":"Department of Endocrinology St Vincent's University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Twomey","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry St Vincent's University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M.","family":"Phillips","sequence":"additional","affiliation":[{"name":"School of Public Health, Physiotherapy and Sports Science University College Dublin  Belfield Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3477-6494","authenticated-orcid":false,"given":"Fionnuala M.","family":"McAuliffe","sequence":"additional","affiliation":[{"name":"UCD Perinatal Research Centre, School of Medicine University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"World Health Organization \u201cNoncommunicable Disease [Webpage] \u201dWorld Health Organization (2023) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/noncommunicable\u2010diseases."},{"key":"e_1_2_13_3_1","unstructured":"World Heart Federation \u201cWomen and Cardiovascular Disease Sweden \u201dWorld Heart Federation (2024) https:\/\/world\u2010heart\u2010federation.org\/what\u2010we\u2010do\/women\u2010cvd\/?petition=close."},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2018-314268"},{"issue":"3","key":"e_1_2_13_5_1","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1001\/jama.2022.23553","article-title":"More Adolescents and Young Adults Developing Type 2 Diabetes Around the World","volume":"329","author":"Larkin H.","year":"2023","journal-title":"JAMA"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0643-8"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001139"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14536"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14523"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17454"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13117"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2020.108625"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-4840-2"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001707"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e5605"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.14310\/horm.2002.1582"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15500"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xagr.2023.100214"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-017-1543-x"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719114525275"},{"key":"e_1_2_13_21_1","unstructured":"T.HaaseandJ.Pratschke \u201cThe 2011 Pobal HP Deprivation Index 2012 \u201dhttps:\/\/maps.pobal.ie\/."},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007038"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/18.6.499"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-36231-7"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13082798"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2020.10.005"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00293.2024"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6080076"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.19.12.1351"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2017.12.010"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.04.023"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2017.10.019"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac212"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwac252"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17740"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0168543"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-024-02184-4"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxaa104"},{"key":"e_1_2_13_39_1","unstructured":"Health Service Executive \u201cStructured Chronic Disease Management Programme Phase 2 \u201dInformation Booklet for General Practitioners."},{"key":"e_1_2_13_40_1","unstructured":"Health Service Executive \u201cEnhanced Community Care: Chronic Disease Management Programme Ireland: Health Service Executive \u201d(2024) https:\/\/www.hse.ie\/eng\/services\/list\/2\/primarycare\/chronic\u2010disease\u2010management\u2010programme\/."},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17975"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14537"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14540"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.10279"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.70092","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1471-0528.70092","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.70092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T23:47:42Z","timestamp":1790552862000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.70092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,24]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/1471-0528.70092"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.70092","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,24]]},"assertion":[{"value":"2025-06-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}