{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T05:44:21Z","timestamp":1775713461300,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2026,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n \n To evaluate the spontaneous clearance of\n \n Mycoplasma genitalium<\/jats:italic>\n <\/jats:styled-content>\n (MG) and associated factors in women.\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Prospective cohort.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Pregnancy termination centre in Bordeaux, France.<\/jats:p>\n <\/jats:sec>\n \n Population<\/jats:title>\n A cohort of 1496 women seeking pregnancy termination.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n MG was detected using self\u2010collected vaginal swabs obtained prior to abortion. Women with concurrent\n \n Chlamydia trachomatis<\/jats:italic>\n <\/jats:styled-content>\n infection or prior intake of antibiotics active against MG were excluded. Demographic, clinical, biological and behavioural data were collected. Follow\u2010up visits were scheduled at 3 and 9\u2009weeks after inclusion, during which self\u2010collected vaginal swabs and sexual behaviour data were collected. MG\u2010positive samples were analysed for bacterial load,\n mpg<\/jats:italic>\n B gene typing, and mutations associated with macrolide and fluoroquinolone resistance.\n <\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n MG negativity at follow\u2010up visits.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Among 1496 women tested, 94 (6.3%) were MG\u2010positive. Of these, 70 met the inclusion criteria, and 75.7% (53 of 70) were asymptomatic. The prevalence of macrolide and fluoroquinolone resistance was 32.3% (11 of 34) and 6% (3 of 50), respectively. Forty\u2010eight women attended follow\u2010up. Spontaneous clearance occurred in 45.8% (22 of 48) of cases throughout the study period. Lower bacterial load at inclusion was the only factor associated with clearance.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The high rate of spontaneous clearance and the substantial prevalence of macrolide resistance support the recommendation against routine MG screening in women presenting for pregnancy termination.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov<\/jats:ext-link>\n identifier: NCT04841408\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1471-0528.70151","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:04:52Z","timestamp":1767855892000},"page":"1074-1082","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous Clearance of Vaginal\n \n Mycoplasma genitalium<\/i>\n <\/scp>\n in Women Undergoing Pregnancy Termination: A Prospective Cohort Study"],"prefix":"10.1111","volume":"133","author":[{"given":"Marie","family":"Berdoyes","sequence":"first","affiliation":[{"name":"CHU Bordeaux, Pregnancy Termination Centre Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9cile","family":"B\u00e9b\u00e9ar","sequence":"additional","affiliation":[{"name":"Bacteriology Department CHU Bordeaux, National Reference Centre for Bacterial Sexually Transmitted Infections Bordeaux France"},{"name":"Univ. Bordeaux, CNRS, MFP, UMR 5234 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chlo\u00e9 Le","family":"Roy","sequence":"additional","affiliation":[{"name":"Univ. Bordeaux, CNRS, MFP, UMR 5234 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Balcon","sequence":"additional","affiliation":[{"name":"Bacteriology Department CHU Bordeaux, National Reference Centre for Bacterial Sexually Transmitted Infections Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Hock\u00e9","sequence":"additional","affiliation":[{"name":"Gynecological Surgery, Medical Gynecology and Reproductive Medicine Department CHU Bordeaux Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dounia","family":"Ba\u00efta","sequence":"additional","affiliation":[{"name":"CHU Bordeaux, Pregnancy Termination Centre Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5358-8990","authenticated-orcid":false,"given":"Olivia","family":"Peuchant","sequence":"additional","affiliation":[{"name":"Bacteriology Department CHU Bordeaux, National Reference Centre for Bacterial Sexually Transmitted Infections Bordeaux France"},{"name":"Univ. Bordeaux, CNRS, MFP, UMR 5234 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053384"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac602"},{"issue":"4","key":"e_1_2_13_4_1","first-page":"254","article-title":"Prevalence of Macrolide and Fluoroquinolone Resistance\u2010Associated Mutations in Mycoplasma genitalium in Metropolitan and Overseas France","volume":"99","author":"Pereyre S.","year":"2023","journal-title":"Sexually Transmitted Infections"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy025"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy922"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02455.x"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae295"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ312"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17972"},{"key":"e_1_2_13_11_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 \u201cTraitement curatif des personnes infect\u00e9es parMycoplasma genitalium\u201d(2025) www.has\u2010sante.fr."},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01023-3"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanmic.2024.101047"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000799"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e31828bfccf"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-35"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2018-053825"},{"key":"e_1_2_13_18_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 \u201cR\u00e9\u00e9valuation de la strat\u00e9gie de d\u00e9pistage des infections \u00e0Chlamydia trachomatis\u201d(2018)."},{"key":"e_1_2_13_19_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9 \u201cInterruption volontaire de grossesse par m\u00e9thode m\u00e9dicamenteuse\u2014Mise \u00e0 jour\u201d(2021)."},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.2.683-692.2004"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2209.160446"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03318-13"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10081587"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2011.09.007"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2016.10.028"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/19396360802042838"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054695"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2007.12.002"},{"issue":"4","key":"e_1_2_13_29_1","first-page":"277","article-title":"The Clinical Indications for Testing Women for Mycoplasma genitalium","volume":"98","author":"Latimer R. 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