{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T18:21:01Z","timestamp":1770661261889,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess temporal trends in outcomes of pregnancies with maternal or paternal type 1 diabetes compared to the general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Register\u2010based study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Denmark.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>1\u2009551\u2009893 pregnancies from 1997 to 2021, hereof 5478 with maternal and 8072 with paternal type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Crude and adjusted logistic regression analyses allowing for interaction between diabetes and time compared outcomes of pregnancies with maternal or paternal type 1 diabetes to the general population and evaluated temporal trends over a 25\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Hypertensive disorders of pregnancy, caesarean delivery, preterm delivery (&lt;\u200937\u2010week gestation), very preterm delivery (&lt;\u200934\u2010week gestation), large for gestational age (LGA) (birth weight\u2009&gt;\u200990th percentile) and extreme LGA (birth weight\u2009&gt;\u200997.5th percentile).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We observed an increasing prevalence of maternal (0.3%\u20130.4%) and paternal (0.5%\u20130.6%) diabetes during the study period. From 1997\u20132001 to 2017\u20132021, pregnancies with maternal diabetes had decreasing odds of preterm delivery (aOR 0.62, 95% CI 0.51;0.74), very preterm delivery (aOR 0.62, 95% CI 0.44;0.87) and extreme LGA (aOR 0.73, 95% CI 0.61;0.88) but remained associated with higher odds of each considered pregnancy outcome in both first and last period (aOR 3.59\u201318.86) compared to the general population. Pregnancies exposed to paternal diabetes were comparable to the general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite a decline in adverse outcomes in pregnancies with maternal type 1 diabetes over the last 25\u2009years, the odds remain greatly increased. These findings support a predominant role of maternal diabetes management rather than parental diabetes genes for pregnancy outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.70174","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T05:16:56Z","timestamp":1770182216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal Trends in Pregnancy Outcomes Among Parents With Type 1 Diabetes: A Nationwide Register\u2010Based Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6037-8510","authenticated-orcid":false,"given":"Tina Wullum","family":"Gundersen","sequence":"first","affiliation":[{"name":"Steno Diabetes Center Zealand Zealand University Hospital  Nykoebing Falster Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sine","family":"Knorr","sequence":"additional","affiliation":[{"name":"Steno Diabetes 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