{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:59:13Z","timestamp":1781153953847,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine whether elevated 1\u2010h plasma glucose (1hPG) during oral glucose tolerance testing is associated with the cross\u2010sectional presence of cardiometabolic risk factors (CMRFs) in normoglycaemic women with polycystic ovary syndrome (PCOS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single\u2010centre.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Population<\/jats:title>\n                    <jats:p>A total of 1152 reproductive\u2010age PCOS women with normal fasting (FPG &lt;\u20095.6\u2009mmol\/L) and 2\u2010h glucose (2hPG &lt;\u20097.8\u2009mmol\/L).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were stratified by 1hPG as normal (&lt;\u20098.6\u2009mmol\/L) or elevated (\u2265\u20098.6\u2009mmol\/L). Prespecified CMRFs (overweight, central obesity, hypertension and dyslipidaemia) were assessed. Associations were examined using univariable and age\u2010adjusted multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Association between elevated 1hPG and the presence of \u2265\u20091 CMRF as well as individual CMRFs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Elevated 1hPG was present in 257\/1152 (22.3%) women and was associated with higher prevalences of overweight, central obesity, and dyslipidaemia, but not hypertension. Elevated 1hPG was associated with \u2265\u20091 CMRF in both crude (OR 2.05, 95% CI 1.44\u20132.91) and age\u2010adjusted analyses (aOR 1.91, 95% CI 1.34\u20132.73; both\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Age\u2010adjusted associations persisted for overweight, central obesity, and dyslipidaemia, but not hypertension. Discrimination for the cross\u2010sectional presence of \u2265\u20091 CMRF was limited, whereas sensitivity was 25.4% and specificity 85.8% at the prespecified threshold of 8.6\u2009mmol\/L.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among normoglycaemic women with PCOS, elevated 1hPG was associated with a less favourable cardiometabolic profile and a higher cross\u2010sectional cardiometabolic risk burden. 1hPG may serve as an adjunct marker within routine OGTT interpretation for early cardiometabolic risk enrichment, but prospective validation is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1471-0528.70219","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T02:26:14Z","timestamp":1773455174000},"page":"1645-1651","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["One\u2010Hour Plasma Glucose and Early Cardiometabolic Risk in Normoglycaemic Women With Polycystic Ovary Syndrome: A Retrospective Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"133","author":[{"given":"Linlin","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Reproductive Medicine Centre, Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Reproductive Medicine Centre, Shenshan Medical Center, Memorial Hospital of Sun Yat\u2010Sen University  Shanwei 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Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Reproductive Medicine Centre, Shenshan Medical Center, Memorial Hospital of Sun Yat\u2010Sen University  Shanwei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9587-1535","authenticated-orcid":false,"given":"Dongzi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Reproductive Medicine Centre, Sun Yat\u2010Sen Memorial Hospital, Sun Yat\u2010Sen University  Guangzhou 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With HbA1c Identifies Individuals With Higher Risk of Cardiovascular Diseases: Cross\u2010Sectional Data From the CATAMERI Study","volume":"35","author":"Fiorentino T. V.","year":"2019","journal-title":"Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy\\"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2021.1902557"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.947292"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.70219","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1471-0528.70219","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.70219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:28:57Z","timestamp":1781152137000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.70219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/1471-0528.70219"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.70219","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"value":"1470-0328","type":"print"},{"value":"1471-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]},"assertion":[{"value":"2025-11-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}