{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T23:24:04Z","timestamp":1771889044243,"version":"3.50.1"},"reference-count":59,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:00:00Z","timestamp":1609113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["1R01HS026001"],"award-info":[{"award-number":["1R01HS026001"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR003017"],"award-info":[{"award-number":["UL1TR003017"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","award":["IHS\u20101409\u201023194"],"award-info":[{"award-number":["IHS\u20101409\u201023194"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Services Research"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This article employs a best\u2010worst scaling (BWS) experiment to identify the claims\u2010based outcomes that matter most to patients and other relevant parties when evaluating pediatric antipsychotic monitoring programs in the United States.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>Patients and relevant parties, with pediatric antipsychotic oversight and treatment experience, completed a BWS experiment, including policymakers (n\u00a0=\u00a031), foster care alumni (n\u00a0=\u00a028), caseworkers (n\u00a0=\u00a023), prescribing clinicians (n\u00a0=\u00a032), and caregivers (n\u00a0=\u00a018).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Respondents received surveys with a scenario on antipsychotic monitoring programs and ranked 11 candidate claims\u2010based outcomes as most and least important for program evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Analysis<\/jats:title><jats:p>Stratified by respondent group, best\u2010worst scores were calculated to identify the relative importance of the claims\u2010based outcomes. A conditional logit examined whether candidate outcomes for safety, quality, and unintended consequences were preferred over reduction in antipsychotic treatment, the outcome used most often to evaluate antipsychotic monitoring programs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Principal Findings<\/jats:title><jats:p>Safety indicators (eg, antipsychotic co\u2010pharmacy, cross\u2010class polypharmacy, higher than recommended doses) ranked among the top three candidate outcomes across respondent groups and were an important complement to antipsychotic treatment reduction. Foster care alumni prioritized \u201cantipsychotic treatment reduction\u201d and \u201cincreased psychosocial treatment.\u201d Caseworkers, prescribers, and caregivers prioritized \u201cincreased follow\u2010up after treatment initiation.\u201d Potential unintended consequences of an antipsychotic monitoring program ranked lowest, including increased use of other psychotropic medication classes (as a substitute), increased psychiatric hospital stays, and increased emergency room utilization. Results of the conditional logit model found only caregivers significantly preferred other indicators over antipsychotic treatment reduction, preferring improvements in follow\u2010up care (5.78) and psychosocial treatment (4.53) and reduction in prescriptions of higher than recommended doses (3.64).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The BWS experiment supported rank ordering of candidate claims\u2010based outcomes demonstrating the opportunity for future studies to align outcomes used in antipsychotic monitoring program evaluations with community preferences, specifically by diversifying metrics to include safety and quality indicators.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1475-6773.13610","type":"journal-article","created":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T21:20:08Z","timestamp":1609190408000},"page":"418-431","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A best\u2010worst scaling experiment to identify patient\u2010centered claims\u2010based outcomes for evaluation of pediatric antipsychotic monitoring programs"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6010-6304","authenticated-orcid":false,"given":"Thomas I.","family":"Mackie","sequence":"first","affiliation":[{"name":"School of Public Health Institute for Health, Health Care Policy and Aging Research Rutgers, The State University of New Jersey Piscataway New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine M.","family":"Kovacs","sequence":"additional","affiliation":[{"name":"School of Public Health Rutgers, The State University of New Jersey Piscataway New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2207-3150","authenticated-orcid":false,"given":"Cassandra","family":"Simmel","sequence":"additional","affiliation":[{"name":"School of Social Work Rutgers, The State University of New Jersey New Brunswick New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0366-7583","authenticated-orcid":false,"given":"Stephen","family":"Crystal","sequence":"additional","affiliation":[{"name":"School of Social Work Institute for Health, Health Care Policy and Aging Research Rutgers, The State University of New Jersey New Brunswick New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4742-8464","authenticated-orcid":false,"given":"Sheree","family":"Neese\u2010Todd","sequence":"additional","affiliation":[{"name":"Institute for Health, Health Care Policy, and Aging Research Rutgers, The State University of New Jersey New Brunswick New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8624-5038","authenticated-orcid":false,"given":"Ayse","family":"Akincigil","sequence":"additional","affiliation":[{"name":"School of Social Work Institute for Health, Health Care Policy and Aging Research Rutgers, The State University of New Jersey New Brunswick New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.11100"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.24.1.163"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1475-6773.13071"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13561-015-0079-x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2012.02.001"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201300525"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201900417"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.28.5.w770"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.childyouth.2011.07.003"},{"key":"e_1_2_7_11_1","volume-title":"Guidance on Strategies to Promote Best Practice in Antipsychotic Prescribing for Children and Adolescents","author":"Mackie TI","year":"2018"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.0500"},{"key":"e_1_2_7_13_1","volume-title":"Foster Children: HHS Guidance could Help States Improve Oversight of Psychotropic Prescriptions","author":"Government Accountability Office","year":"2011"},{"key":"e_1_2_7_14_1","volume-title":"Children's Mental Health: Concerns Remain about Appropriate Services for Children in Medicaid and Foster Care","author":"Government Accountability Office","year":"2012"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201300455"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2013.0094"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2010.11.005"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200932040-00006"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-016-0721-x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2019.04.022"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.0763"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1361"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200302000-00008"},{"key":"e_1_2_7_24_1","article-title":"Practice parameter for the use of atypical antipsychotic medications in children and adolescents","author":"Findling R","year":"2011","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2011.156"},{"key":"e_1_2_7_26_1","unstructured":"Canadian Institute for Health Research.CAMESA Guidelines.2018;http:\/\/camesaguideline.org\/about\u2010the\u2010guidelines. Accessed August 9 2018."},{"issue":"2","key":"e_1_2_7_27_1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1542\/9781581108088-pediatric_psychopharmacology","article-title":"Pediatric psychopharmacology in primary care: a conceptual framework","volume":"24","author":"Riddle MA","year":"2013","journal-title":"Adolescent Med State Art Rev"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1360"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e31805371bf"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2014.06.013"},{"key":"e_1_2_7_31_1","unstructured":"FinnertyM KealeyR KlimaJ et al.Development of a suite of antipsychotic measures for youth in medicaid and in foster care. Paper presented at: Academy Health Annual Research2013; Baltimore MD."},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2018.24.3.238"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867415600891"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijresmar.2012.10.002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.7001.376"},{"issue":"1","key":"e_1_2_7_36_1","first-page":"10","article-title":"The Delphi technique: making sense of consensus","volume":"12","author":"Hsu C\u2010C","year":"2007","journal-title":"Pract Assess Res Evaluat"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/074391569201100202"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhealeco.2006.04.002"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-006-0096-5"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-015-0633-1"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548732.2011.542728"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-8-75"},{"key":"e_1_2_7_43_1","first-page":"19","article-title":"Unintended outcomes of Medicaid drug cost\u2010containment policies on the chronically mentally ill","volume":"64","author":"Soumerai S","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_7_44_1","unstructured":"National Committee for Quality Assurance.Healthcare Effectiveness Data and Information Set (HEDIS) 2018 Volume 2: Technical specifications for health plans. Metabolic monitoring for children and adolescents on antipsychotics (APM).2018.http:\/\/www.ncqa.org\/hedis\u2010quality\u2010measurement\/hedis\u2010measures\/hedis\u20102018. Accessed November 11 2018."},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-3442"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201400343"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.4135\/9781412983655"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.79.8.1053"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15327752jpa4803_13"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-8-76"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1017\/S026646231200027X"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2012.1176"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2016.0064"},{"key":"e_1_2_7_54_1","article-title":"Systematic review: systems\u2010wide interventions to monitor pediatric antipsychotic prescribing and promote best practice","author":"Mackie TI","year":"2020","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"e_1_2_7_55_1","article-title":"The debate over rational decision making in evidence\u2010based medicine: implications for evidence\u2010informed policy","author":"Sheldrick RC","year":"2019","journal-title":"Evid Policy J Res Debate Practice"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2010.48"},{"key":"e_1_2_7_57_1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1542\/peds.113.S1.185","article-title":"Measuring the quality of children's health care: a prerequisite to action","volume":"113","author":"Dougherty D","year":"2004","journal-title":"Pediatrics"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2014.06.025"},{"key":"e_1_2_7_59_1","volume-title":"Antipsychotic Medication Use in Children and Adolescents: Report and Resource Guide from a 16\u2010state Study","author":"Medicaid Medical Directors Learning Network and Rutgers Center for Education and Research on Mental Health Therapeutics","year":"2010"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201400343"}],"container-title":["Health Services Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1475-6773.13610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1475-6773.13610","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1475-6773.13610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T10:29:05Z","timestamp":1693304945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1475-6773.13610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,28]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/1475-6773.13610"],"URL":"https:\/\/doi.org\/10.1111\/1475-6773.13610","archive":["Portico"],"relation":{},"ISSN":["0017-9124","1475-6773"],"issn-type":[{"value":"0017-9124","type":"print"},{"value":"1475-6773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,28]]},"assertion":[{"value":"2020-12-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}