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Outcomes included high\u2010dosage opioids, overlapping opioid prescriptions, concurrent opioid\/benzodiazepines, opioids from &gt;3 prescribers, opioids from &gt;3 pharmacies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Extraction Methods<\/jats:title><jats:p>We identified all prescription opioid dispensing to Black and White adults aged 18\u201364 without a palliative care or cancer diagnosis code.<\/jats:p><\/jats:sec><jats:sec><jats:title>Principal Findings<\/jats:title><jats:p>Exactly 7,096,592 White and 1,167,310 Black individuals met inclusion criteria. Pain management clinic laws were associated with reductions in two outcomes; their association with high\u2010dosage receipt was larger among White patients. In contrast, reductions due to PDMP mandates appeared limited to, or larger in, Black patients compared with White patients in four of five outcomes. For example, PDMP mandates reduced high\u2010dosage receipt in Black patients by 0.7 percentage points (95% CI: 0.36\u20131.08\u2009ppt.) over 4\u2009years: an 8.4% decrease from baseline; there was no apparent effect in White patients. Similarly, while there was limited evidence that mandates reduced overlapping opioid receipt in White patients, they appeared to reduce overlapping opioid receipt in Black patients by 1.3\u00a0ppt. (95% CI: \u22121.66\u2013\u22121.01\u2009ppt.) across post\u2010policy years\u2014a 14.4% decrease from baseline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PDMP prescriber check mandates but not pain management clinic laws appeared to reduce opioid dispensing more in Black patients than White patients. Future research should discern the mechanisms underlying these disparities and their consequences for pain management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1475-6773.13968","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T04:10:35Z","timestamp":1646367035000},"page":"482-496","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Did prescribing laws disproportionately affect opioid dispensing to Black patients?"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7459-9798","authenticated-orcid":false,"given":"Tarlise N.","family":"Townsend","sequence":"first","affiliation":[{"name":"Department of Health Management and Policy University of Michigan  Ann Arbor Michigan USA"},{"name":"NYU Grossman School of Medicine, Department of Population Health Center for Opioid Epidemiology and Policy  New York New York USA"},{"name":"NYU Rory Meyers College of Nursing  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy S. 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