{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T12:53:43Z","timestamp":1762520023547,"version":"3.30.2"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1995,9,1]],"date-time":"1995-09-01T00:00:00Z","timestamp":809913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"vor","delay-in-days":7425,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[1995,9]]},"DOI":"10.1111\/1523-1747.ep12321097","type":"journal-article","created":{"date-parts":[[2004,7,12]],"date-time":"2004-07-12T20:44:19Z","timestamp":1089665059000},"page":"411-417","source":"Crossref","is-referenced-by-count":41,"title":["Matrix Metalloproteinases in Blood Vessel Development in Human Fetal Skin and in Cutaneous Tumors"],"prefix":"10.1016","volume":"105","author":[{"given":"Tatiana V.","family":"Karelina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory I.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur Z.","family":"Eisen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/1523-1747.ep12321097_bb0010","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1096\/fasebj.5.8.1850705","article-title":"Matrix metalloproteinases and their inhibitors in connective tissue remodeling","volume":"5","author":"Woessner","year":"1991","journal-title":"FASEB J"},{"key":"10.1111\/1523-1747.ep12321097_bb0015","series-title":"Regulatory Mechanisms in Breast Cancer","first-page":"421","article-title":"Extracellular matrix metalloproteinases in tumor inva-sion and metastasis","author":"Goldberg","year":"1991"},{"key":"10.1111\/1523-1747.ep12321097_bb0020","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1083\/jcb.95.3.974","article-title":"Plasminogen activator and collagenase production by cultured capillary endothelial cells","volume":"95","author":"Gross","year":"1982","journal-title":"J Cell Biol"},{"key":"10.1111\/1523-1747.ep12321097_bb0025","doi-asserted-by":"crossref","first-page":"2814","DOI":"10.1016\/S0021-9258(17)35860-X","article-title":"Secretion of metallo-proteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors","volume":"261","author":"Herron","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0030","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1016\/S0021-9258(17)35859-3","article-title":"Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity","volume":"261","author":"Herron","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0035","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/jcp.1041530324","article-title":"Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo","volume":"153","author":"Grant","year":"1992","journal-title":"J Cell Pysiol"},{"key":"10.1111\/1523-1747.ep12321097_bb0040","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/dbio.1994.1104","article-title":"Interstitial collagenase is required for angiogenesis in vitro","volume":"162","author":"Fisher","year":"1994","journal-title":"Dev Biol"},{"key":"10.1111\/1523-1747.ep12321097_bb0045","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1083\/jcb.119.2.475","article-title":"Isolation and characterization of an inhibitor of neovascularizarion from scapular chondrocytes","volume":"119","author":"Moses","year":"1992","journal-title":"J Cell Biol"},{"key":"10.1111\/1523-1747.ep12321097_bb0050","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/0006-291X(90)90822-5","article-title":"Induction of angiogenesis in chick yolk-sac membrane by polyamines and its inhibition by tissue inhibitors of metalloproteinases TIMP and TIMP-2","volume":"171","author":"Takigawa","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1111\/1523-1747.ep12321097_bb0055","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0092-8674(85)90104-7","article-title":"Tumor-promoting phorbol esters induce angiogenesis in vitro","volume":"42","author":"Montesano","year":"1985","journal-title":"Cell"},{"key":"10.1111\/1523-1747.ep12321097_bb0060","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0092-8674(80)90620-0","article-title":"Tetradecanoyl phorbol acetate stimulates latent collagenase production by cultured human endothelial cells","volume":"20","author":"Moscatelli","year":"1980","journal-title":"Cell"},{"key":"10.1111\/1523-1747.ep12321097_bb0065","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1073\/pnas.80.9.2623","article-title":"Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro","volume":"80","author":"Gross","year":"1983","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/1523-1747.ep12321097_bb0070","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/jcb.240470308","article-title":"A metalloproteinase inhibitor as an inhibitor of neovas-cularization","volume":"47","author":"Moses","year":"1991","journal-title":"J Cell Biochem"},{"key":"10.1111\/1523-1747.ep12321097_bb0075","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/0006-291X(92)91118-A","article-title":"Selective endothelial growth inhibition by tetracyclines that inhibit collagenase","volume":"188","author":"Guerin","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1111\/1523-1747.ep12321097_bb0080","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1126\/science.1694043","article-title":"Identification of an inhibitor of neovascularization from cartilage","volume":"248","author":"Moses","year":"1990","journal-title":"Science"},{"key":"10.1111\/1523-1747.ep12321097_bb0085","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.4049\/jimmunol.143.5.1619","article-title":"Effect of tumor necrosis factor and epidermal growth factor on cell morphology, cell surface receptors, and the production of tissue inhibitor of metalloproteinases and IL-6 in human microvascular endothelial cells","volume":"143","author":"Mawatari","year":"1989","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12321097_bb0090","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0021-9258(19)40250-0","article-title":"Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloprotein-ases by endothelial cells","volume":"265","author":"Unemori","year":"1990","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0095","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/jcp.1041560204","article-title":"Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro","volume":"156","author":"Schnaper","year":"1993","journal-title":"J Cell Physiol"},{"key":"10.1111\/1523-1747.ep12321097_bb0100","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1073\/pnas.86.8.2632","article-title":"Tissue cooperation in a proteolytic cascade activating human interstitial collagenase","volume":"86","author":"He","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/1523-1747.ep12321097_bb0105","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1016\/S0021-9258(18)42873-6","article-title":"Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin","volume":"267","author":"Goldberg","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0110","first-page":"6184","article-title":"Independent expression and cellular processing of Mr 72,000 type IV colla- genase and interstitial collagenase in human tumorigenic cell lines","volume":"50","author":"Brown","year":"1990","journal-title":"Cancer Res"},{"key":"10.1111\/1523-1747.ep12321097_bb0115","doi-asserted-by":"crossref","first-page":"17213","DOI":"10.1016\/S0021-9258(18)71480-4","article-title":"SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collage- nase which is identical to that secreted by normal human macrophages","volume":"264","author":"Wilhelm","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0120","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/jnci\/84.13.1017","article-title":"Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in B16-F10 melanoma cells","volume":"84","author":"Khokha","year":"1992","journal-title":"J Natl Cancer Inst"},{"key":"10.1111\/1523-1747.ep12321097_bb0125","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/BF00133464","article-title":"Up-regulation of TIMP-1 expression in B 16-F10 melanoma cells suppresses their metastatic ability in chick embryo","volume":"10","author":"Khokha","year":"1992","journal-title":"Clin Exp Metastasis"},{"key":"10.1111\/1523-1747.ep12321097_bb0130","first-page":"701","article-title":"Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases","volume":"52","author":"DeClerck","year":"1992","journal-title":"Cancer Res"},{"key":"10.1111\/1523-1747.ep12321097_bb0135","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1126\/science.2465572","article-title":"Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells","volume":"243","author":"Khokha","year":"1989","journal-title":"Science"},{"key":"10.1111\/1523-1747.ep12321097_bb0140","doi-asserted-by":"crossref","first-page":"9087","DOI":"10.1016\/S0021-9258(19)50392-1","article-title":"The matrix metalloproteinase matrilysin (PUMP) is expressed in developing human mononuclear phagocytes","volume":"267","author":"Busiek","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1111\/1523-1747.ep12321097_bb0145","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/1523-1747.ep12395596","article-title":"Matrilysin (PUMP) correlates with dermal invasion during appendageal development and cutaneous neoplasia","volume":"103","author":"Karelina","year":"1994","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12321097_bb0150","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/1523-1747.ep12462791","article-title":"Localization of 92-kDa type IV collagenase in human skin tumors: comparison with normal human fetal and adult skin","volume":"100","author":"Karelina","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12321097_bb0155","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/1523-1747.ep12580896","article-title":"Development of human embryonic and fetal dermalvasculature","volume":"93","author":"Johnson","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12321097_bb0160","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1164\/ajrccm\/140.4.1097","article-title":"Embryonic origins and assembly of blood vessels","volume":"140","author":"Noden","year":"1989","journal-title":"Am Rev Respir"},{"key":"10.1111\/1523-1747.ep12321097_bb0165","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1097\/00006534-198506000-00017","article-title":"Histologie study of recurrent basal cell carcinoma","volume":"75","author":"Dellon","year":"1985","journal-title":"Plast Reconstr Surg"},{"key":"10.1111\/1523-1747.ep12321097_bb0170","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1001\/archderm.1973.01620180049015","article-title":"Recurrent skin cancer","volume":"107","author":"Freeman","year":"1973","journal-title":"Arch Dermatol"},{"key":"10.1111\/1523-1747.ep12321097_bb0175","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1259\/0007-1285-66-783-181","article-title":"Angiogenesis, neovascular proliferation and vascular pathophysi-ology as targets for cancer therapy","volume":"66","author":"Denekamp","year":"1993","journal-title":"Br J Radiol"},{"key":"10.1111\/1523-1747.ep12321097_bb0180","first-page":"302","article-title":"Review of current applications in tumor prognostication","volume":"10","author":"Weidner","year":"1993","journal-title":"Semin Diagn Pathol"},{"key":"10.1111\/1523-1747.ep12321097_bb0185","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1146\/annurev.ph.49.030187.002321","article-title":"Mechanisms of angiogenesis","volume":"49","author":"D'Amore","year":"1987","journal-title":"Annu Rev' Physiol"},{"key":"10.1111\/1523-1747.ep12321097_bb0190","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/jcp.1041020209","article-title":"Studies of morpho-logically atypical (\u201csprouting\u201d) cultures of bovine aortic endothelial cells. Growth characteristics and connective tissue protein synthesis","volume":"102","author":"Cotta-Pereira","year":"1980","journal-title":"J Cell Physiol"},{"key":"10.1111\/1523-1747.ep12321097_bb0195","first-page":"624","article-title":"Mechanisms of neovascularization\/vascular sprouting can occur without proliferation of en-dothelial cells","volume":"51","author":"Sholley","year":"1984","journal-title":"Lab Invest"},{"key":"10.1111\/1523-1747.ep12321097_bb0200","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0026-2862(77)90141-8","article-title":"Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis","volume":"14","author":"Ausprunk","year":"1977","journal-title":"Microvasc Res"},{"key":"10.1111\/1523-1747.ep12321097_bb0205","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0922-3371(90)90046-Y","article-title":"Proteolytic balance and capillary morphogenesis","volume":"32","author":"Pepper","year":"1990","journal-title":"Cell Differ Dev"},{"key":"10.1111\/1523-1747.ep12321097_bb0210","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/aja.1001750409","article-title":"Collagen types I, III and V in human embryonic and fetal skin","volume":"175","author":"Smith","year":"1986","journal-title":"Am J Anat"},{"key":"10.1111\/1523-1747.ep12321097_bb0215","first-page":"1188","article-title":"Correlation of intratumoral endothelial cell proliferation with microvessel density (tumor angiogenesis) and tumor cell proliferation in breast carcinoma","volume":"144","author":"Vartanian","year":"1994","journal-title":"Am J Pathol"},{"key":"10.1111\/1523-1747.ep12321097_bb0220","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1093\/jnci\/84.24.1875","article-title":"Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma","volume":"84","author":"Weidner","year":"1992","journal-title":"J Natl Cancer Inst"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15423176?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X15423176?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T21:38:14Z","timestamp":1734471494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X15423176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["S0022202X15423176"],"URL":"https:\/\/doi.org\/10.1111\/1523-1747.ep12321097","relation":{},"ISSN":["0022-202X"],"issn-type":[{"type":"print","value":"0022-202X"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}