{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T06:10:09Z","timestamp":1772259009993,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1990,6,1]],"date-time":"1990-06-01T00:00:00Z","timestamp":644198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":9315,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Investigative Dermatology"],"published-print":{"date-parts":[[1990,6]]},"DOI":"10.1111\/1523-1747.ep12874666","type":"journal-article","created":{"date-parts":[[2004,7,19]],"date-time":"2004-07-19T15:34:33Z","timestamp":1090251273000},"page":"808-811","source":"Crossref","is-referenced-by-count":179,"title":["Ultraviolet Light Induces Increased Circulating Interleukin-6 in Humans"],"prefix":"10.1016","volume":"94","author":[{"given":"Agatha","family":"Urbanski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Neuner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Krutmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Kirnbauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A","family":"Luger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"K\u00f6ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/1523-1747.ep12874666_bb0010","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/1523-1747.ep12580362","article-title":"Fever and increased serum IL-1 activity as a systemic manifestation of acute phototoxicity in New Zealand white rabbits","volume":"89","author":"Ansel","year":"1987","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/1011-1344(89)80097-1","article-title":"Effect of UV irradiation on epidermal cell cytokine production","volume":"4","author":"Schwarz","year":"1989","journal-title":"J Photochem Photobiol"},{"key":"10.1111\/1523-1747.ep12874666_bb0020","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.4049\/jimmunol.142.7.2321","article-title":"Endotoxemia elicits increased circulating \u03b22-interferon\/interleukin-6 in man","volume":"142","author":"Fong","year":"1989","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12874666_bb0025","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0167-5699(88)91200-5","article-title":"Multiple actions of interleukin 6 within a cytokine network","volume":"9","author":"Wong","year":"1988","journal-title":"Immunol Today"},{"key":"10.1111\/1523-1747.ep12874666_bb0030","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0140-6736(87)91413-9","article-title":"Serum levels of interleukin-6 and acute phase response","volume":"2","author":"Nijsten","year":"1987","journal-title":"Lancet"},{"key":"10.1111\/1523-1747.ep12874666_bb0035","first-page":"490A","article-title":"Monocytes derived from patients with psoriasis synthesize and release increased levels of interleukin 6","volume":"92","author":"Neuner","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0040","doi-asserted-by":"crossref","first-page":"948","DOI":"10.4049\/jimmunol.142.3.948","article-title":"Interferon \u03b22\/interleukin 6 in plasma and body fluids during acute bacterial infection","volume":"142","author":"Helfgott","year":"1989","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12874666_bb0045","first-page":"123","article-title":"The serum interleukin 6 response to elective surgery","volume":"8","author":"Shenkin","year":"1989","journal-title":"Lymphokine Res"},{"key":"10.1111\/1523-1747.ep12874666_bb0050","unstructured":"Luger T.A. Schwarz T: Epidermal cell derived cytokines.In: Bos J (ed). Skin Immune System CRC Press, Boca Rotan (in press)"},{"key":"10.1111\/1523-1747.ep12874666_bb0055","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.4049\/jimmunol.142.6.1922","article-title":"IFN-\u03b22, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines","volume":"142","author":"Kirnbauer","year":"1989","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12874666_bb0060","first-page":"459A","article-title":"Different effects of UVA and UVB irradiation of epidermal cell-IL 6 expression and release","volume":"92","author":"Kirnbauer","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0065","first-page":"1507","article-title":"Preventive treatment of sunburn dermatoheliosis and skin cancer with sunprotective agents","author":"Pathak","year":"1987"},{"key":"10.1111\/1523-1747.ep12874666_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2133.1977.tb05177.x","article-title":"Phototesting and dosimetry for photochemotherapy","volume":"96","author":"Wolff","year":"1977","journal-title":"Br J Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0075","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/1523-1747.ep12522862","article-title":"The effect of in vitro and in vivo irradiation on the production of ETAF activity by human and murine keratinocytes","volume":"81","author":"Ansel","year":"1983","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0080","first-page":"187","article-title":"Whole-body exposure to ultraviolet radiation results in increased serum interleukin-1 activity in humans","volume":"3","author":"Granstein","year":"1987","journal-title":"Lymphokine Res"},{"key":"10.1111\/1523-1747.ep12874666_bb0085","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/1523-1747.ep12276763","article-title":"Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis","volume":"92","author":"Konnikov","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0090","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1084\/jem.167.3.1253","article-title":"B cell stimulatory factor 2\/interleukin 6 is a costimulant for human thymocytes and T lymphocytes","volume":"167","author":"Lotz","year":"1988","journal-title":"J Exp Med"},{"key":"10.1111\/1523-1747.ep12874666_bb0095","first-page":"29","article-title":"Structure, genetics and function of human \u201c\u03b22-interferon\/B-cell stimulatory factor-2\/hepatocyte stimulating factor\u201d (interleukin-6)","author":"Santhanam","year":"1988"},{"key":"10.1111\/1523-1747.ep12874666_bb0100","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.4049\/jimmunol.142.5.1542","article-title":"IL-6\/IFN-\u03b22 as a circulating hormone","volume":"142","author":"Jablons","year":"1989","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12874666_bb0105","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0190-9622(86)70017-0","article-title":"Immunology and photocarcinogenesis","volume":"14","author":"Kripke","year":"1986","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0110","first-page":"284","article-title":"Immunological consequence of UV radiation exposure","volume":"3","author":"Roberts","year":"1986","journal-title":"Photodermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0115","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/1523-1747.ep12276652","article-title":"Effects of UV radiation on autoimmune strains of mice: Increased mortality and accelerated autoimmunity in BXSB male mice","volume":"85","author":"Ansel","year":"1985","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0120","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/1523-1747.ep12676722","article-title":"Intradermal anti-prostaglandin agents and sunburn","volume":"62","author":"Snyder","year":"1974","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0125","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/1523-1747.ep12696708","article-title":"Inhibition of the induction of contact hypersensitivity by a UV-mediated epidermal cytokine","volume":"87","author":"Schwarz","year":"1986","journal-title":"J Invest Dermatol"},{"key":"10.1111\/1523-1747.ep12874666_bb0130","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.4049\/jimmunol.138.5.1457","article-title":"UV-irradiated epidermal cells produce a specific inhibitor of interleukin 1 activity","volume":"138","author":"Schwarz","year":"1987","journal-title":"J Immunol"},{"key":"10.1111\/1523-1747.ep12874666_bb0135","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/1523-1747.ep12476889","article-title":"Detection of a specific inhibitor of interleukin 1 in sera of UVB-treated mice","volume":"91","author":"Schwarz","year":"1988","journal-title":"J Invest Dermatol"}],"container-title":["Journal of Investigative Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X9090074G?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022202X9090074G?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T01:04:59Z","timestamp":1682730299000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022202X9090074G"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,6]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1990,6]]}},"alternative-id":["S0022202X9090074G"],"URL":"https:\/\/doi.org\/10.1111\/1523-1747.ep12874666","relation":{},"ISSN":["0022-202X"],"issn-type":[{"value":"0022-202X","type":"print"}],"subject":[],"published":{"date-parts":[[1990,6]]}}}