{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T21:13:16Z","timestamp":1785532396927,"version":"3.56.0"},"reference-count":167,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:00:00Z","timestamp":1503446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Comp Rev Food Sci Food Safe"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The presence of mycotoxins in foodstuff causes serious health problems to consumers and economically affects the food industry. Among the mycotoxins, aflatoxins are very toxic and highly carcinogenic contaminants which affect the safety of many foods, and therefore endanger human health. Aflatoxin M\n                    <jats:sub>1<\/jats:sub>\n                    (AFM\n                    <jats:sub>1<\/jats:sub>\n                    ) found in milk results from the biotransformation of aflatoxin B\n                    <jats:sub>1<\/jats:sub>\n                    . Many efforts have been made to control the source of AFM\n                    <jats:sub>1<\/jats:sub>\n                    from farmers to dairy product companies. However, AFM\n                    <jats:sub>1<\/jats:sub>\n                    escapes ordinary methods of food treatment such as cooking, sterilization, and freezing, hence it appears in milk and dairy products. The presence of high levels of AFM\n                    <jats:sub>1<\/jats:sub>\n                    constitutes an alarming threat as milk and dairy products contain essential nutrients for human health, especially for infants and children. For this reason, there is a pressing need for developing a fast and reliable screening method for detecting trace aflatoxins in food. Several analytical methods based on high\u2010performance liquid chromatography (HPLC) and mass spectroscopy have been used for aflatoxin detection; however, they are expensive, time\u2010consuming, and require many skills. Recently, immunoassay methods, including enzyme\u2010linked immunosorbent assay (ELISA), immunosensors, and lateral flow immunoassay (LFIA), have been preferred for food analysis because of their improved qualities such as high sensitivity, simplicity, and capability of onsite monitoring. This paper reviews the new developments and applications of immunoassays for the rapid detection of AFM\n                    <jats:sub>1<\/jats:sub>\n                    in milk.\n                  <\/jats:p>","DOI":"10.1111\/1541-4337.12287","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T06:22:40Z","timestamp":1503469360000},"page":"808-820","source":"Crossref","is-referenced-by-count":91,"title":["Current Immunoassay Methods for the Rapid Detection of Aflatoxin in Milk and Dairy Products"],"prefix":"10.1111","volume":"16","author":[{"given":"Emmanuel","family":"Matabaro","sequence":"first","affiliation":[{"name":"Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology Jiangnan Univ.  Wuxi Jiangsu 214122 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestor","family":"Ishimwe","sequence":"additional","affiliation":[{"name":"Hefei Natl. Laboratory for Physical Sciences at Microscale and School of Life Sciences Univ. of Science and Technology of China  Hefei Anhui 230027 China"},{"name":"the Dept. of Chemistry, College of Science and Technology Univ. of Rwanda  Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Uwimbabazi","sequence":"additional","affiliation":[{"name":"School of Food Science Jiangnan Univ.  Wuxi Jiangsu 214122 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9142-2273","authenticated-orcid":false,"given":"Byong H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Dept. of Microbiology and Immunology McGill Univ.  Montreal QC H3A 2B4 Canada"},{"name":"Dept. of Food Science and Biotechnology Kangwon Natl. Univ.  Chuncheon 200701 South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.02.027"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1541-4337.12029"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2010.01.029"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.coac.2016.03.022"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-096532-1.01309-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.5772\/51777"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2013.02.020"},{"key":"e_1_2_7_9_1","volume-title":"Regulatory limits of mycotoxins in ASEAN countries","author":"ASEAN","year":"2015"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2014.01.037"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2012.04.012"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2004.05.068"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2016.06.006"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cofs.2015.09.002"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2009.11.014"},{"key":"e_1_2_7_16_1","first-page":"241","volume-title":"Aflatoxins: recent advances and future prospects","author":"Bbosa GS","year":"2013"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac401729y"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2014.06.021"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2016.04.022"},{"key":"e_1_2_7_20_1","first-page":"363","volume-title":"Comprehensive analytical chemistry","author":"Brera C","year":"2008"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins5010173"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2014.08.003"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-85709-801-6.00003-4"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2005.12.003"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2016.04.007"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfda.2016.02.002"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2014.12.009"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2016.03.004"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-804308-0.00012-1"},{"key":"e_1_2_7_30_1","unstructured":"ChinaGB.2015.GB2761\u20102011 Food Safety National Standard for Maximum Levels of Mycotoxins in Food. 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